Vaccines for African swine fever: An update

H Zhang, S Zhao, H Zhang, Z Qin, H Shan… - Frontiers in …, 2023 - frontiersin.org
African swine fever (ASF) is a fatal infectious disease of swine caused by the African swine
fever virus (ASFV). Currently, the disease is listed as a legally notifiable disease that must be …

Current status and evolving approaches to African swine fever vaccine development

T Teklue, Y Sun, M Abid, Y Luo… - … and emerging diseases, 2020 - Wiley Online Library
African swine fever (ASF) is a highly lethal haemorrhagic disease of swine caused by
African swine fever virus (ASFV), a unique and genetically complex virus. The disease …

pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production

J Li, J Song, L Kang, L Huang, S Zhou, L Hu… - PLoS …, 2021 - journals.plos.org
Inflammatory factors and type I interferons (IFNs) are key components of host antiviral innate
immune responses, which can be released from the pathogen-infected macrophages …

Development of a highly effective African swine fever virus vaccine by deletion of the I177L gene results in sterile immunity against the current epidemic Eurasia strain

MV Borca, E Ramirez-Medina, E Silva, E Vuono… - Journal of …, 2020 - Am Soc Microbiol
African swine fever virus (ASFV) is the etiological agent of a contagious and often lethal
disease of domestic pigs that has significant economic consequences for the swine industry …

African swine fever virus vaccine candidate ASFV‐G‐ΔI177L efficiently protects European and native pig breeds against circulating Vietnamese field strain

XH Tran, TTP Le, QH Nguyen, TT Do… - Transboundary and …, 2022 - Wiley Online Library
The recent spread of African swine fever (ASF) in the People's Republic of China and
neighbouring countries in Asia has had significant economic consequences with an …

Deletion of the A137R gene from the pandemic strain of African swine fever virus attenuates the strain and offers protection against the virulent pandemic virus

DP Gladue, E Ramirez-Medina, E Vuono… - Journal of …, 2021 - Am Soc Microbiol
African swine fever virus (ASFV) is causing a devastating pandemic in domestic and wild
swine within an extended geographical area from Central Europe to East Asia, resulting in …

African swine fever virus E120R protein inhibits interferon beta production by interacting with IRF3 to block its activation

H Liu, Z Zhu, T Feng, Z Ma, Q Xue, P Wu, P Li… - Journal of …, 2021 - Am Soc Microbiol
African swine fever is a devastating disease of swine caused by African swine fever virus
(ASFV). The pathogenesis of the disease remains largely unknown, leaving the spread of …

A cell culture-adapted vaccine virus against the current African swine fever virus pandemic strain

MV Borca, A Rai, E Ramirez-Medina, E Silva… - Journal of …, 2021 - Am Soc Microbiol
African swine fever virus (ASFV) causes a virulent, deadly infection in wild and domestic
swine and is currently causing a pandemic covering a contiguous geographical area from …

African swine fever vaccines: a promising work still in progress

L Bosch-Camós, E López, F Rodriguez - Porcine health management, 2020 - Springer
African swine fever (ASF), a disease of obligatory declaration to the World Organization for
Animal Health (OIE), has contributed to poverty and underdevelopment of affected areas …

[HTML][HTML] Therapeutic potentials of CRISPR-Cas genome editing technology in human viral infections

S Najafi, SC Tan, S Aghamiri, P Raee… - Biomedicine & …, 2022 - Elsevier
Viral infections are a common cause of morbidity worldwide. The emergence of Coronavirus
Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel …