Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer
K English, A Shepherd, NE Uzor, R Trinh… - Acta Neuropathologica …, 2020 - Springer
Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are
associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used …
associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used …
Calcium-binding proteins in the nervous system during hibernation: neuroprotective strategies in hypometabolic conditions?
G Gattoni, G Bernocchi - International Journal of Molecular Sciences, 2019 - mdpi.com
Calcium-binding proteins (CBPs) can influence and react to Ca2+ transients and modulate
the activity of proteins involved in both maintaining homeostatic conditions and protecting …
the activity of proteins involved in both maintaining homeostatic conditions and protecting …
Long-term effects after treatment with platinum compounds, cisplatin and [Pt (O, O′-acac)(γ-acac)(DMS)]: autophagy activation in rat B50 neuroblastoma cells
M Grimaldi, V Dal Bo, B Ferrari, E Roda… - Toxicology and Applied …, 2019 - Elsevier
Cisplatin (cisPt), among the best known components of multi-drug front-line therapies used
for the treatments of solid tumors, such as the childhood neuroblastoma, acts through DNA …
for the treatments of solid tumors, such as the childhood neuroblastoma, acts through DNA …
Probing the interaction of cisplatin with calmodulin and its effect upon binding to myosin light-chain kinase
S Yuan, S Wang, K Cao, Y Wang, H Hu… - Inorganic Chemistry …, 2025 - pubs.rsc.org
Despite the successful clinical application of cisplatin, its mechanism of action and adverse
effects remain poorly understood. To elucidate the complex pharmacology of this drug …
effects remain poorly understood. To elucidate the complex pharmacology of this drug …
[Pt(O,O'-acac)(γ-acac)(DMS)]: Alternative Strategies to Overcome Cisplatin-Induced Side Effects and Resistance in T98G Glioma Cells
Cisplatin (CDDP) is one of the most effective chemotherapeutic agents, used for the
treatment of diverse tumors, including neuroblastoma and glioblastoma. CDDP induces cell …
treatment of diverse tumors, including neuroblastoma and glioblastoma. CDDP induces cell …
Platinum Deposition in the Central Nervous System: A Novel Insight into Oxaliplatin-induced Peripheral Neuropathy in Young and Old Mice
AS Reis, JJ Paltian, WB Domingues, DLR Novo… - Molecular …, 2024 - Springer
Numerous factors can contribute to the incidence or exacerbation of peripheral neuropathy
induced by oxaliplatin (OXA). Recently, platinum accumulation in the spinal cord of mice …
induced by oxaliplatin (OXA). Recently, platinum accumulation in the spinal cord of mice …
Nanoporous Platinum Microelectrode Arrays for Neuroscience Applications
N Winter-Hjelm, L Isdal, PA Köllensperger, A Sandvig… - bioRxiv, 2024 - biorxiv.org
Microelectrode arrays are invaluable tools for investigating the electrophysiological
behaviour of neuronal networks with high spatiotemporal precision. In recent years, it has …
behaviour of neuronal networks with high spatiotemporal precision. In recent years, it has …
Neurotoxicity of Cisplatin as Monotherapy or Combined Chemotherapy in Cancer Treatment
AN Volpini, IJ de Souza Marques… - Clinical Cancer …, 2022 - benthamdirect.com
Introduction: The main toxicity of cisplatin is nephrotoxicity, but more and more studies have
highlighted and unveiled the mechanisms of cisplatin toxicity, and the neurotoxicity has …
highlighted and unveiled the mechanisms of cisplatin toxicity, and the neurotoxicity has …
[HTML][HTML] The role of ionic homeostasis in cisplatin-induced neurotoxicity: A preliminary study
Objective: The aim of the present study was to investigate the role of ionic homeostasis in
cisplatin (cisdiamminedichloroplatinum (II), CDDP)-induced neurotoxicity. CDDP is a …
cisplatin (cisdiamminedichloroplatinum (II), CDDP)-induced neurotoxicity. CDDP is a …
Toxicities of therapeutic agents used in medicine
VA Carozzi, G Cavaletti - Toxics, 2016 - mdpi.com
This Special Issue on “Toxicities of Therapeutic Agents Used in Medicine” reports on some
peculiar cases of toxicities related to widely and commonly employed drugs. Side effects are …
peculiar cases of toxicities related to widely and commonly employed drugs. Side effects are …