Endometrial immune dysfunction in recurrent pregnancy loss

C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

Orchestrated leukocyte recruitment to immune-privileged sites: absolute barriers versus educational gates

R Shechter, A London, M Schwartz - Nature Reviews Immunology, 2013 - nature.com
Complex barriers separate immune-privileged tissues from the circulation. Here, we propose
that cell entry to immune-privileged sites through barriers composed of tight junction …

Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells

O Parolini, F Alviano, GP Bagnara, G Bilic… - Stem …, 2008 - academic.oup.com
Placental tissue draws great interest as a source of cells for regenerative medicine because
of the phenotypic plasticity of many of the cell types isolated from this tissue. Furthermore …

Human leukocyte antigen (HLA) and immune regulation: how do classical and non-classical HLA alleles modulate immune response to human immunodeficiency …

NB Crux, S Elahi - Frontiers in immunology, 2017 - frontiersin.org
The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …

HLA‐G and immune tolerance in pregnancy

JS Hunt, MG Petroff, RH McIntire, C Ober - The FASEB Journal, 2005 - Wiley Online Library
Multiple mechanisms underlie the surprising willingness of mothers to tolerate genetically
different fetal tissues during pregnancy. Chief among these is the choice of HLA‐G, a gene …

A critical role for the programmed death ligand 1 in fetomaternal tolerance

I Guleria, A Khosroshahi, MJ Ansari, A Habicht… - The Journal of …, 2005 - rupress.org
Fetal survival during gestation implies that tolerance mechanisms suppress the maternal
immune response to paternally inherited alloantigens. Here we show that the inhibitory T …

See no evil, hear no evil, do no evil: the lessons of immune privilege

JY Niederkorn - Nature immunology, 2006 - nature.com
Immune-mediated inflammation and allograft rejection are greatly reduced in certain organs,
a phenomenon called'immune privilege'. Immune privilege is well developed in three …

Gimme shelter: the immune system during pregnancy

A Munoz‐Suano, AB Hamilton… - Immunological reviews, 2011 - Wiley Online Library
Antigen‐presenting molecules vary between individuals of the same species, making it more
difficult for pathogens to evade immune recognition and spread through the whole …

HLA-G: too much or too little? Role in cancer and autoimmune disease

JM Martín-Villa, C Vaquero-Yuste… - Frontiers in …, 2022 - frontiersin.org
HLA-G is a non-classical HLA class I molecule with immunomodulatory properties. It was
initially described at the maternal-fetal interface, and it was later found that this molecule …

A balancing act: mechanisms by which the fetus avoids rejection by the maternal immune system

JC Warning, SA McCracken, JM Morris - Reproduction, 2011 - rep.bioscientifica.com
The main objectives of this study were to determine the influence of diets enriched in α-
linolenic, linoleic or oleic acid on the development and transcriptomic profile of embryos …