Anti-inflammatory activity of triazine derivatives: A systematic review

L Marín-Ocampo, LA Veloza, R Abonia… - European Journal of …, 2019 - Elsevier
Triazines are heterocyclic compounds with a variety of biological activities that have been
increasingly studied in recent years due to their versatile structure (three isoforms) and the …

[PDF][PDF] 1, 2, 4-triazine analogs as novel class of therapeutic agents

R Kumar, TS Sirohi, H Singh, R Yadav… - Mini-Rev. Med …, 2014 - researchgate.net
Abstract: 1, 2, 4-Triazine nucleus is a prominent structural core system present in numerous
pharmacologically active compounds. Till date, various 1, 2, 4-triazine analogs, possesing a …

Synthesis and biological evaluation of thieno [2′, 3′: 4, 5] pyrimido [1, 2-b][1, 2, 4] triazines and thieno [2, 3-d][1, 2, 4] triazolo [1, 5-a] pyrimidines as anti …

HM Ashour, OG Shaaban, OH Rizk… - European Journal of …, 2013 - Elsevier
A new series of thieno [2′, 3′: 4, 5] pyrimido [1, 2-b][1, 2, 4] triazines and thieno [2, 3-d][1,
2, 4] triazolo [1, 5-a] pyrimidines was synthesized. The newly synthesized compounds were …

Synthesis, antiviral, DFT and molecular docking studies of some novel 1, 2, 4-triazine nucleosides as potential bioactive compounds

AI Khodair, A Ahmed, DR Imam, NA Kheder… - Carbohydrate …, 2021 - Elsevier
A novel series of nucleosides with potential antiviral activity have been synthesized and
characterized using IR, MS, 1D NMR and 2D NMR data. The antiviral activity of the …

Microwave assisted synthesis of some new fused 1, 2, 4-triazines bearing thiophene moieties with expected pharmacological activity

HA Saad, MM Youssef, MA Mosselhi - Molecules, 2011 - mdpi.com
Rapid and efficient solvent-free synthesis of 4-amino-3-mercapto-6-[2-(2-thienyl) vinyl]-1, 2,
4-triazin-5 (4 H)-one 1 under microwave irradiation is described. Some new fused …

Design, synthesis, and pharmacological evaluation of aryl oxadiazole linked 1, 2, 4-triazine derivatives as anticonvulsant agents

G Grover, R Pal, R Bhatia, MS Yar, R Nath… - Medicinal Chemistry …, 2022 - Springer
A series of new clubbed aryl oxadiazole-1, 2, 4-triazine derivatives (6a-l) were designed and
synthesized using appropriate chemical routes. The structures were designed to have the …

Design, synthesis, biological evaluation, and molecular docking study on triazine based derivatives as anti-inflammatory agents

P Asadi, M Alvani, V Hajhashemi, M Rostami… - Journal of Molecular …, 2021 - Elsevier
In an attempt to develop new anti-inflammatory agents, design, synthesis, pharmacological
activities, and docking study of two groups of triazine-based derivatives were reported. Nine …

The Effect of Novel 7-methyl-5-phenyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine Sulfonamide Derivatives on Apoptosis and Autophagy in DLD-1 and HT-29 Colon …

A Gornowicz, A Szymanowska, M Mojzych… - International Journal of …, 2020 - mdpi.com
The discovery of cytotoxic drugs is focused on designing a compound structure that directly
affects cancer cells without an impact on normal cells. The mechanism of anticancer activity …

Potent anticancer and antimicrobial activities of pyrazole, oxazole and pyridine derivatives containing 1, 2, 4-triazine moiety

AS Abd El-All, SA Osman, HMF Roaiah… - Medicinal Chemistry …, 2015 - Springer
Due to the importance of biological activities of 1, 2, 4-triazine derivatives, in this manuscript,
ten of newly synthesized compounds containing 1, 2, 4-triazine moiety were prepared …

Heterocyclic compounds bearing triazine scaffold and their biological significance: A review

T Verma, M Sinha, N Bansal - Anti-Cancer Agents in Medicinal …, 2020 - ingentaconnect.com
Benzene is a six-membered hydrocarbon ring system and if three carbon-hydrogen units of
benzene ring are replaced by nitrogen atoms then triazine is formed. Triazines are present …