Histamine: a mediator of intestinal disorders—a review

S Smolinska, E Winiarska, A Globinska, M Jutel - Metabolites, 2022 - mdpi.com
Within the gastrointestinal tract, histamine is present at relatively high concentrations,
especially during inflammatory processes. Histamine is a biogenic amine with numerous …

Food intolerance: the role of histamine

YO Shulpekova, VM Nechaev, IR Popova, TA Deeva… - Nutrients, 2021 - mdpi.com
Histamine is a natural amine derived from L-histidine. Although it seems that our knowledge
about this molecule is wide and diverse, the importance of histamine in many regulatory …

Histamine-producing bacteria and their role in gastrointestinal disorders

M Fiorani, LE Del Vecchio, P Dargenio… - Expert Review of …, 2023 - Taylor & Francis
Introduction Gut microbiota produces thousands of metabolites, which have a huge impact
on the host health. Specific microbial strains are able to synthesize histamine, a molecule …

Histamine in cancer immunology and immunotherapy. Current status and new perspectives

MP Sarasola, MA Taquez Delgado… - Pharmacology …, 2021 - Wiley Online Library
Cancer is the second leading cause of death globally and its incidence and mortality are
rapidly increasing worldwide. The dynamic interaction of immune cells and tumor cells …

The taxonomic distribution of histamine-secreting bacteria in the human gut microbiome

Z Mou, Y Yang, AB Hall, X Jiang - BMC genomics, 2021 - Springer
Background Biogenic histamine plays an important role in immune response,
neurotransmission, and allergic response. Although endogenous histamine production has …

[HTML][HTML] Current and novel approaches in the pharmacological treatment of hepatocellular carcinoma

F Villarruel-Melquiades… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most lethal malignant tumours worldwide. The
mortality-to-incidence ratio is up to 91.6% in many countries, representing the third leading …

Lactobacillus reuteri in digestive system diseases: focus on clinical trials and mechanisms

Y Peng, Y Ma, Z Luo, Y Jiang, Z Xu… - Frontiers in cellular and …, 2023 - frontiersin.org
Objectives Digestive system diseases have evolved into a growing global burden without
sufficient therapeutic measures. Lactobacillus reuteri (L. reuteri) is considered as a new …

Characterization of immune landscape in papillary thyroid cancer reveals distinct tumor immunogenicity and implications for immunotherapy

J Sun, R Shi, X Zhang, D Fang, J Rauch, S Lu… - …, 2021 - Taylor & Francis
Although the vast majority of patients with papillary thyroid cancer (PTC) have a favorable
prognosis when conventional treatments are implemented, local recurrence and distant …

High‐fat diet promotes prostate cancer growth through histamine signaling

M Matsushita, K Fujita, K Hatano… - … Journal of Cancer, 2022 - Wiley Online Library
Western high‐fat diets (HFD) are regarded as a major risk factor for prostate cancer (PCa).
Using prostate‐specific Pten‐knockout mice as a PCa model, we previously reported that …

[HTML][HTML] Phylogenetically diverse bacterial species produce histamine

KA Engevik, A Hazzard, B Puckett, KM Hoch… - Systematic and Applied …, 2024 - Elsevier
Histamine is an important biogenic amine known to impact a variety of patho-physiological
processes ranging from allergic reactions, gut-mediated anti-inflammatory responses, and …