Quantitative measurement of functional activity of the PI3K signaling pathway in cancer

A van de Stolpe - Cancers, 2019 - mdpi.com
The phosphoinositide 3-kinase (PI3K) growth factor signaling pathway plays an important
role in embryonic development and in many physiological processes, for example the …

RNA based approaches to profile oncogenic pathways from low quantity samples to drive precision oncology strategies

A Van De Stolpe, W Verhaegh, JY Blay, CX Ma… - Frontiers in …, 2021 - frontiersin.org
Precision treatment of cancer requires knowledge on active tumor driving signal
transduction pathways to select the optimal effective targeted treatment. Currently only a …