Differentiated thyroid cancers are more frequent in women than in men. These different
frequencies may depend on differences in patient's behavior and in thyroid investigations …

Hashimoto's thyroiditis (HT) is the most common autoimmune disease in humans frequently
leading to hypothyroidism. HT is characterized by a cellular immune response with …

Abstract Thyroid hormones (TH) 3, 5, 3′, 5'-tetraiodothyronine or thyroxine (T4) and 3, 5, 3'-
triiodothyronine (T3) contain iodine atoms as part of their structure, and their synthesis occur …

Background: An in-depth understanding of the fundamental principles that regulate thyroid
hormone homeostasis is critical for the development of new diagnostic and treatment …

Thyroid hormones (THs), including T4 and T3, are produced and released by the thyroid
gland under the stimulation of thyroid-stimulating hormone (TSH). The homeostasis of THs is …

Secondary ion mass spectrometry (SIMS) constitutes an extremely sensitive technique for
imaging surfaces in 2D and 3D. Apart from its excellent sensitivity and high lateral resolution …

In thyrocytes, cell polarity is of crucial importance for proper thyroid function. Many intrinsic
mechanisms of self-regulation control how the key players involved in thyroid hormone (TH) …

Thyroid peroxidase (TPO) is the key enzyme involved in thyroid hormone synthesis.
Autoantibodies to TPO (TPOAbs) are a hallmark of autoimmune thyroid disease (AITD) …

Background: The established paradigm for thyroglobulin (Tg) function is that of a high
molecular weight precursor of the much smaller thyroid hormones, triiodothyronine (T3) and …

Caveolins are a family of membrane proteins required for the formation of small plasma
membrane invaginations called caveolae that are implicated in cellular trafficking processes …