Among the many heavy metals, chromium (Cr) is one of the fascinating ones. In its two most
prevalent oxidation forms, trivalent (Cr 3+) and hexavalent (Cr 6+), Cr has completely …

Abstract Heavy metal Chromium (Cr), can adversely affect humans and their health if
accumulated in organs of the body, such as the lungs, liver, and kidneys. Cr (VI) is highly …

In recent years, several drugs have been developed deriving from traditional products and
current drug research is actively investigating the possible therapeutic roles of many …

It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …

Oxidative stress and inflammation are mediators in the development and progression of
chronic kidney disease (CKD) and its complications, and they are inseparably linked as …

For years, there have been studies based on the use of natural compounds plant-derived as
potential therapeutic agents for various diseases in humans. Curcumin is a phenolic …

Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Chromium has two main valence states: hexavalent chromium (Cr [VI]) and trivalent
chromium (Cr [III]). Cr (VI), a well-established human carcinogen, can enter cells by way of a …

The transcription factor NF-E2-related factor 2 (Nrf2) is a master regulator of a genetic
program, termed the phase 2 response, that controls redox homeostasis and participates in …

Over 10% of the global population suffers from kidney disease. However, only kidney
replacement therapies, which burden medical expenses, are currently effective in treating …