The scanning model for eukaryotic mRNA translation initiation states that the small
ribosomal subunit, along with initiation factors, binds at the cap structure at the 5′ end of …

Cellular stress is an intrinsic part of cell physiology that underlines cell survival or death. The
ability of mammalian cells to regulate global protein synthesis (aka translational control) …

Recently, the World Health Organization confirmed 120 new human cases of avian H7N9
influenza in China resulting in 37 deaths, highlighting the concern for a potential pandemic …

Protein translation typically begins with the recruitment of the 43S ribosomal complex to the
5′ cap of mRNAs by a cap-binding complex. However, some transcripts are translated in a …

In eukaryotic cells, protein synthesis typically begins with the binding of eIF4F to the 7-
methylguanylate (m 7 G) cap found on the 5′ end of the majority of mRNAs. Surprisingly …

Cells have developed different mechanisms to respond to stress, including the formation of
cytoplasmic foci known as stress granules (SGs). SGs are dynamic and formed as a result of …

SARS‐CoV‐2 has become a pandemic worldwide; therefore, an effective vaccine is urgently
needed. Recently, messenger RNAs (mRNAs) have emerged as a promising platform for …

Abstract Stress-induced angiogenin (ANG)-mediated tRNA cleavage promotes a cascade of
cellular events that starts with production of tRNA-derived stress-induced RNAs (tiRNAs) …

Eukaryotic translation initiation relies on the m 7 G cap present at the 5′ end of all mRNAs.
Some viral mRNAs employ alternative mechanisms of initiation based on internal ribosome …

Viruses exploit the translation machinery of an infected cell to synthesize their proteins.
Therefore, viral mRNAs have to compete for ribosomes and translation factors with cellular …