Stroke is currently the second most common cause of death worldwide and a major cause of
serious long-term morbidity. Selenium is a trace element with pleotropic effects on human …

Abstract 3, 3′, 4′, 4′, 5-Polychlorinated biphenyls (PCB126) is classified as a persistent
organic environmental pollutant that can cause liver damage by producing excessive …

Polychlorinated biphenyls (PCBs), a group of 209 congeners that differ in the number and
position of chlorines on the biphenyl ring, are anthropogenic chemicals that belong to the …

Polychlorinated biphenyls (PCBs) are endocrine disrupting chemicals with documented,
though mechanistically ill-defined, reproductive toxicity. The toxicity of dioxin-like PCBs …

Metabolic syndrome (MetS) is the most common adverse drug reaction from psychiatric
pharmacotherapy. Neuroreceptor blockade by the antipsychotic drug clozapine induces …

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in the
regulation of biological responses to more planar aromatic hydrocarbons, like TCDD. We …

Epidemiological and laboratory studies link polychlorinated biphenyls and their metabolites
to adverse neurodevelopmental outcomes. Several neurotoxic PCB congeners are chiral …

Glutathione transferases (GSTs) are phase II enzymes that detoxify a wide range of toxicants
and reactive intermediates. One such class of toxicants is the ubiquitous polycyclic aromatic …

Potent aryl hydrocarbon receptor agonists like PCB 126 (3, 3′, 4, 4′, 5-
pentachlorobiphenyl) cause oxidative stress and liver pathology, including fatty liver. Our …

Abstract 3, 3′, 4, 4′, 5-pentachlorobiphenyl (PCB126), a dioxin-like PCB, elicits toxicity
through a wide array of noncarcinogenic effects, including metabolic syndrome, wasting …