Essential oils (EOs) have been traditionally used as ancient remedies to treat many health
disorders due to their enormous biological activities. As mainstream allopathic medication …

Extensive research into prodrug modification of active pharmaceutical ingredients and
nanoparticle drug delivery systems has led to unprecedented levels of control over the …

Limited solubility and hepatic first-pass metabolism are the main causes of low
bioavailability of anti-schizophrenic drug, Clozapine (CZP). The objective of the study was to …

Background The interest in the use of Eucalyptus genus members, in parallel with preclinical
studies has been steadily growing over the last few decades in the field of pharmaceuticals …

Hyaluronic acid (HA), as a hygroscopic and biocompatible molecule, has displayed unique
permeation enhancement in transdermal delivery systems. Hence, indomethacin (IND) was …

Myrtaceae is one of the most important plants families, being regarded as the eighth largest
flowering plant family. It includes many genera of utmost ecological and economical …

Introduction Nanoemulsion-based drug delivery approaches have witnessed massive
acceptance over the years and acquired a significant foothold owing to their tremendous …

The active compounds from essential oils have been an important asset in treating different
diseases for many centuries. Nowadays, there are various available formulations used as …

Essential oils have been proposed as promising non-toxic transdermal permeation
enhancers. Their use is limited because of their low water solubility. The use of …

Lemon essential oil (LEO) is a kind of citrus essential oil with antioxidant, anti-inflammatory,
and antimicrobial activities, but low water solubility and biological instability hinder its …