A review of reaction enhancement strategies for isothermal nucleic acid amplification reactions

B Özay, SE McCalla - Sensors and Actuators Reports, 2021 - Elsevier
Isothermal nucleic acid amplification techniques are used to detect a variety of molecules
such as RNAs, DNAs and proteins. When compared to the gold standard polymerase chain …

Twinkle-catalyzed toehold-mediated DNA strand displacement reaction

A Singh, G Patel, SS Patel - Journal of the American Chemical …, 2023 - ACS Publications
Strand exchange between homologous nucleic acid sequences is the basis for cellular DNA
repair, recombination, and genome editing technologies. Specialized enzymes catalyze …

Accelerating DNA-based computing on a supramolecular polymer

W Engelen, SPW Wijnands… - Journal of the American …, 2018 - ACS Publications
Dynamic DNA-based circuits represent versatile systems to perform complex computing
operations at the molecular level. However, the majority of DNA circuits relies on freely …

Coupling hybridization chain reaction with catalytic hairpin assembly enables non-enzymatic and sensitive fluorescent detection of microRNA cancer biomarkers

Y Wei, W Zhou, X Li, Y Chai, R Yuan, Y Xiang - Biosensors and …, 2016 - Elsevier
The identification and quantification of sequence-specific microRNAs (miRNAs) plays an
important role in early diagnosis of different diseases. In this work, by integrating two …

Catalytic DNA polymerization can be expedited by active product release

PG Moerman, M Gavrilov, T Ha… - Angewandte …, 2022 - Wiley Online Library
The sequence‐specific hybridization of DNA facilitates its use as a building block for
designer nanoscale structures and reaction networks that perform computations. However …

Polymer-catalyzed DNA assembly relies on weak non-covalent interactions

J Hu, T Tong, P Shi, J Weng, X Xu, X Cao… - Cell Reports Physical …, 2024 - cell.com
In general, molecular interactions with high binding affinities are preferred when
constructing self-assembly systems. Herein, we demonstrate that weak non-covalent …

Enhancement of RecA-mediated self-assembly in DNA nanostructures through basepair mismatches and single-strand nicks

SL Corbett, R Sharma, AG Davies, C Wälti - Scientific Reports, 2017 - nature.com
The use of DNA as a structural material for nanometre-scale construction has grown
extensively over the last decades. The development of more advanced DNA-based …

Modelling and verification for DNA nanotechnology

F Dannenberg - 2016 - ora.ox.ac.uk
DNA nanotechnology is a rapidly developing field that creates nanoscale devices from DNA,
which enables novel interfaces with biological material. Their therapeutic use is envisioned …

Dynamic Stabilization of DNA Assembly by Using Pyrrole‐Imidazole Polyamide

YS Ang, T Bando, H Sugiyama, LYL Yung - ChemBioChem, 2020 - Wiley Online Library
We used N‐methylpyrrole (Py)‐N‐methylimidazole‐(Im) polyamide as an exogenous agent
to modulate the formation of DNA assemblies at specific double‐stranded sequences. The …

Development and Characterization of a Novel Isothermal DNA Amplification Reaction

B Ozay - 2021 - search.proquest.com
Isothermal nucleic acid amplification chemistries are gaining popularity as nucleic acid
detection tools that can replace the current gold standard methods, PCR and its derivatives …