[HTML][HTML] Mesoporous silica nanoparticles for therapeutic/diagnostic applications

S Jafari, H Derakhshankhah, L Alaei, A Fattahi… - Biomedicine & …, 2019 - Elsevier
Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as
high surface area, large pore size, good biocompatibility and biodegradability, stable …

Recent advances of cocktail chemotherapy by combination drug delivery systems

Q Hu, W Sun, C Wang, Z Gu - Advanced drug delivery reviews, 2016 - Elsevier
Combination chemotherapy is widely exploited for enhanced cancer treatment in the clinic.
However, the traditional cocktail administration of combination regimens often suffers from …

Challenges associated with penetration of nanoparticles across cell and tissue barriers: a review of current status and future prospects

S Barua, S Mitragotri - Nano today, 2014 - Elsevier
Nanoparticles (NPs) have emerged as an effective modality for the treatment of various
diseases including cancer, cardiovascular and inflammatory diseases. Various forms of NPs …

Enzyme-responsive nanomaterials for controlled drug delivery

Q Hu, PS Katti, Z Gu - Nanoscale, 2014 - pubs.rsc.org
Enzymes underpin physiological function and exhibit dysregulation in many disease-
associated microenvironments and aberrant cell processes. Exploiting altered enzyme …

Nanoparticle–hydrogel superstructures for biomedical applications

Y Jiang, N Krishnan, J Heo, RH Fang… - Journal of Controlled …, 2020 - Elsevier
The incorporation of nanoparticles into hydrogels yields novel superstructures that have
become increasingly popular in biomedical research. Each component of these nanoparticle …

Microfluidic-assisted fabrication of carriers for controlled drug delivery

D Liu, H Zhang, F Fontana, JT Hirvonen, HA Santos - Lab on a Chip, 2017 - pubs.rsc.org
The microfluidic technique has brought unique opportunities toward the full control over the
production processes for drug delivery carriers, owing to the miniaturisation of the fluidic …

Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy

W Li, Z Liu, F Fontana, Y Ding, D Liu… - Advanced …, 2018 - Wiley Online Library
In the past two decades, porous silicon (PSi) has attracted increasing attention for its
potential biomedical applications. With its controllable geometry, tunable nanoporous …

Small interfering RNA (siRNA) to target genes and molecular pathways in glioblastoma therapy: Current status with an emphasis on delivery systems

S Mirzaei, MK Mahabady, A Zabolian, A Abbaspour… - Life Sciences, 2021 - Elsevier
Glioblastoma multiforme (GBM) is one of the worst brain tumors arising from glial cells,
causing many deaths annually. Surgery, chemotherapy, radiotherapy and immunotherapy …

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

Nanoformulations for combination or cascade anticancer therapy

L Miao, S Guo, CM Lin, Q Liu, L Huang - Advanced drug delivery reviews, 2017 - Elsevier
Nanoparticle drug formulations have been extensively investigated, developed, and in some
cases, approved by the Food and Drug Administration (FDA). Synergistic combinations of …