TOP-GAN: Stain-free cancer cell classification using deep learning with a small training set

M Rubin, O Stein, NA Turko, Y Nygate, D Roitshtain… - Medical image …, 2019 - Elsevier
We propose a new deep learning approach for medical imaging that copes with the problem
of a small training set, the main bottleneck of deep learning, and apply it for classification of …

Differential diagnosis of hereditary anemias from a fraction of blood drop by digital holography and hierarchical machine learning

P Memmolo, G Aprea, V Bianco, R Russo… - Biosensors and …, 2022 - Elsevier
Anemia affects about the 25% of the global population and can provoke severe diseases,
ranging from weakness and dizziness to pregnancy problems, arrhythmias and hearth …

Automatic classification of red blood cell morphology based on quantitative phase imaging

M Jiang, M Shao, X Yang, L He, T Peng… - … Journal of Optics, 2022 - Wiley Online Library
Classification of the morphology of red blood cells (RBCs) plays an extremely important role
in evaluating the quality of long‐term stored blood, as RBC storage lesions such as …

Automatic detection and characterization of quantitative phase images of thalassemic red blood cells using a mask region-based convolutional neural network

YH Lin, KYK Liao, KB Sung - Journal of Biomedical Optics, 2020 - spiedigitallibrary.org
Significance: Label-free quantitative phase imaging is a promising technique for the
automatic detection of abnormal red blood cells (RBCs) in real time. Although deep-learning …

Fast automated quantitative phase reconstruction in digital holography with unsupervised deep learning

S Park, Y Kim, I Moon - Optics and Lasers in Engineering, 2023 - Elsevier
Digital holography can provide quantitative phase images related to the morphology and
content of biological samples. To reconstruct an accurate phase image, several processes …

Quantitative analysis of three-dimensional morphology and membrane dynamics of red blood cells during temperature elevation

K Jaferzadeh, MW Sim, NG Kim, IK Moon - Scientific Reports, 2019 - nature.com
The optimal functionality of red blood cells is closely associated with the surrounding
environment. This study was undertaken to analyze the changes in membrane profile, mean …

Quantification of stored red blood cell fluctuations by time-lapse holographic cell imaging

K Jaferzadeh, I Moon, M Bardyn, M Prudent… - Biomedical optics …, 2018 - opg.optica.org
We propose methods to quantitatively calculate the fluctuation rate of red blood cells with
nanometric axial and millisecond temporal sensitivity at the single-cell level by using time …

Deep learning-based phenotypic assessment of red cell storage lesions for safe transfusions

E Kim, S Park, S Hwang, I Moon… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
This study presents a novel approach to automatically perform instant phenotypic
assessment of red blood cell (RBC) storage lesion in phase images obtained by digital …

Automated phase reconstruction and super-resolution with deep learning in digital holography

S Park, Y Kim, I Moon - Optics & Laser Technology, 2024 - Elsevier
Digital holography can provide quantitative phase images that are related to the shape and
content of biological samples. In particular, high-resolution phase images contain more …

Automated quantitative analysis of multiple cardiomyocytes at the single‐cell level with three‐dimensional holographic imaging informatics

I Moon, K Jaferzadeh, E Ahmadzadeh… - Journal of …, 2018 - Wiley Online Library
Cardiomyocytes derived from human pluripotent stem cells are a promising tool for disease
modeling, drug compound testing, and cardiac toxicity screening. Bio‐image segmentation …