Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update

AV Noordegraaf, KM Chin, F Haddad… - European …, 2019 - Eur Respiratory Soc
The function of the right ventricle determines the fate of patients with pulmonary
hypertension. Since right heart failure is the consequence of increased afterload, a full …

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary …

M Humbert, G Kovacs, MM Hoeper… - European heart …, 2022 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association …

B Pieske, C Tschöpe, RA De Boer… - European heart …, 2019 - academic.oup.com
Making a firm diagnosis of chronic heart failure with preserved ejection fraction (HFpEF)
remains a challenge. We recommend a new stepwise diagnostic process, the 'HFA–PEFF …

Impact of COVID-19 on exercise pathophysiology: a combined cardiopulmonary and echocardiographic exercise study

C Baratto, S Caravita, A Faini… - Journal of Applied …, 2021 - journals.physiology.org
Survivors from COVID-19 pneumonia can present with persisting multisystem involvement
(lung, pulmonary vessels, heart, muscle, red blood cells) that may negatively affect exercise …

The physiological basis of pulmonary arterial hypertension

R Naeije, MJ Richter, LJ Rubin - European Respiratory Journal, 2022 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a rare dyspnoea-fatigue syndrome caused by a
progressive increase in pulmonary vascular resistance and eventual right ventricular (RV) …

[HTML][HTML] Haemodynamic definitions and updated clinical classification of pulmonary hypertension

G Simonneau, D Montani… - European respiratory …, 2019 - Eur Respiratory Soc
Since the 1st World Symposium on Pulmonary Hypertension (WSPH) in 1973, pulmonary
hypertension (PH) has been arbitrarily defined as mean pulmonary arterial pressure …

An official European Respiratory Society statement: pulmonary haemodynamics during exercise

G Kovacs, P Herve, JA Barbera… - European …, 2017 - Eur Respiratory Soc
There is growing recognition of the clinical importance of pulmonary haemodynamics during
exercise, but several questions remain to be elucidated. The goal of this statement is to …

Pulmonary hypertension in heart failure: pathophysiology, pathobiology, and emerging clinical perspectives

M Guazzi, R Naeije - Journal of the American College of Cardiology, 2017 - jacc.org
Pulmonary hypertension is a common hemodynamic complication of heart failure. Interest in
left-sided pulmonary hypertension has increased remarkably in recent years because its …

The overloaded right heart and ventricular interdependence

R Naeije, R Badagliacca - Cardiovascular research, 2017 - academic.oup.com
The right and the left ventricle are interdependent as both structures are nested within the
pericardium, have the septum in common and are encircled with common myocardial fibres …

Pulmonary vascular hemodynamic response to exercise in cardiopulmonary diseases

GD Lewis, E Bossone, R Naeije, E Grünig, R Saggar… - Circulation, 2013 - Am Heart Assoc
The inherent assumptions of the PVR equation are that (mPAP− LAP)/CO relationships are
linear and cross the line of origin. If these assumptions are correct, PVR should be …