Nitrative difunctionalization of alkenes via cobalt-mediated radical ligand transfer and radical-polar crossover photoredox catalysis

S Patra, R Giri, D Katayev - ACS Catalysis, 2023 - ACS Publications
Herein, we report the rational design of a modular dual photoredox and cobalt catalysis
paradigm for the difunctionalization of unsaturated hydrocarbons, unlocking the synthesis of …

Site-Selective Nitration of Aryl Germanes at Room Temperature

A Dahiya, AG Gevondian, A Selmani… - Organic …, 2023 - ACS Publications
We report a site-selective ipso-nitration of aryl germanes in the presence of boronic esters,
silanes, halogens, and additional functionalities. The protocol is characterized by …

A unified flow strategy for the preparation and use of trifluoromethyl-heteroatom anions

M Spennacchio, M Bernús, J Stanić, D Mazzarella… - Science, 2024 - science.org
The trifluoromethyl group (CF3) is a key functionality in pharmaceutical and agrochemical
development, greatly enhancing the efficacy and properties of resulting compounds …

Overcoming Challenges in O‐Nitration: Selective Alcohol Nitration Deploying N,6‐Dinitrosaccharin and Lewis Acid Catalysis

AJ Fernandes, V Valsamidou… - Angewandte Chemie …, 2024 - Wiley Online Library
Nitrate esters hold pivotal roles in pharmaceuticals, energetic materials, and atmospheric
processes, motivating the development of efficient synthesis routes. Here, we present a …

Facile Access to Terminal Nitroalkanes via Anti‐Markovnikov Hydronitration and Hydronitroalkylation of Alkenes Using Photoredox Catalysis

S Patra, D Katayev - Chemistry–A European Journal, 2024 - Wiley Online Library
The evolution of catalysis and functional group transfer reagents play a significant role in the
development of anti‐Markovnikov alkene hydrofunctionalization reactions, facilitating the …

Copper-Catalyzed Formal Dihydrosilylation of Terminal Alkynes: AC (sp)–H Silylation-Hydrosilylation-Hydrogenation Sequence

J Li, S Fang, S Ge - ACS Catalysis, 2024 - ACS Publications
Copper-catalyzed regioselective double anti-Markovnikov hydrosilylation of terminal alkynes
has been developed by employing a copper catalyst generated from readily available …

Late-Stage C–H Nitration of Unactivated Arenes by Fe(NO3)3·9H2O in Hexafluoroisopropanol

Y Zheng, QQ Hu, Q Huang, Y Xie - Organic Letters, 2024 - ACS Publications
Operationally simple and generally applicable arene nitration with cheap and easily
accessible chemicals has been a long-sought transformation in the synthetic organic …

Mechanochemistry Drives Alkene Difunctionalization via Radical Ligand Transfer and Electron Catalysis

S Patra, BN Nandasana, V Valsamidou… - Advanced …, 2024 - Wiley Online Library
A general and modular protocol is reported for olefin difunctionalization through
mechanochemistry, facilitated by cooperative radical ligand transfer (RLT) and electron …

An efficient Cu catalyzed regioselective Ortho-nitration approach for the synthesis of 2-nitroarylcyanamides: Molecular docking and ADME studies

SNM Boddapati, R Tamminana, HJ Senapathi… - Journal of Molecular …, 2025 - Elsevier
Copper catalyzed regio-selective organic functional group insertions have been developed
as a prevailing tool in organic synthesis. In this work, we report a regio-selective ortho …

Simplifying Nitration Chemistry with Bench-stable Organic Nitrating Reagents

S Patra, V Valsamidou, D Katayev - Chimia, 2024 - chimia.ch
Nitro compounds play a crucial role in academia and industries, serving as building blocks
for the synthesis of drugs, agrochemicals, and materials. Nitration, a fundamental process in …