Imaging mass spectrometry has become a mature molecular mapping technology that is
used for molecular discovery in many medical and biological systems. While powerful by …

Novel profiling methodologies are redefining the diagnostic capabilities and therapeutic
approaches towards more precise and personalized healthcare. Complementary …

Many studies have demonstrated that tissue phenotyping (tissue typing) based on mass
spectrometric imaging data is possible; however, comprehensive studies assessing …

Background Imaging mass spectrometry enables in situ label-free detection of thousands of
metabolites from intact tissue samples. However, automated steps for multi-omics analyses …

Aerobic life is based on numerous metabolic oxidation reactions as well as biosynthesis of
oxygenated signaling compounds. Among the latter are the myriads of oxygenated lipids …

Vaccines represent one of the major advances of modern medicine. Despite the many
successes of vaccination, continuous efforts to design new vaccines are needed to fight “old” …

The study of biological specimens by mass spectrometry imaging (MSI) has had a profound
influence in the various forms of spatial-omics over the past two decades including …

Simple Summary Diagnostic subtyping of non-small cell lung cancer is paramount for
therapy stratification. Our study shows that the subtyping into pulmonary adenocarcinoma …

Simple Summary Tumor treatment is heavily dictated by the tumor progression status.
However, in colon cancer, it is difficult to predict disease progression in the early stages. In …

(1) Background: Therapeutic blocking of the interaction between programmed death-1 (PD-
1) with its ligand PD-L1, an immune checkpoint, is a promising approach to restore the …