[HTML][HTML] Purinergic receptors in cognitive disturbances

P Illes, H Ulrich, JF Chen, Y Tang - Neurobiology of Disease, 2023 - Elsevier
Purinergic receptors (Rs) of the ATP/ADP, UTP/UDP (P2X, P2Y) and adenosine (A1, A2A)-
sensitive classes broadly interfere with cognitive processes both under quasi normal and …

[HTML][HTML] Role of A1 adenosine receptor in cardiovascular diseases: Bridging molecular mechanisms with therapeutic opportunities

W Parichatikanond, R Duangrat… - Experimental and …, 2025 - Elsevier
Adenosine serves as a critical homeostatic regulator, exerting influence over physiological
and pathological conditions in the cardiovascular system. During cellular stress, increased …

Effect of Acute Hypoxia Exposure on the Availability of A1 Adenosine Receptors and Perfusion in the Human Brain

M Michno, J Schmitz, AL Foerges… - Journal of Nuclear …, 2025 - jnm.snmjournals.org
In animal studies it has been observed that the inhibitory neuromodulator adenosine is
released into the cerebral interstitial space during hypoxic challenges. Adenosine's actions …

Myelin Imaging of the Spinal Cord in Animal Models and Patients with Multiple Sclerosis Using [11C] MeDAS PET: A Translational Study

CWJ van der Weijden, AKMA Ahmed… - Journal of Nuclear …, 2025 - jnm.snmjournals.org
Multiple sclerosis (MS) is a neurodegenerative disease characterized by demyelinated
lesions in the brain and spinal cord. A few clinical studies using PET to image myelin in the …

Spreading of tau protein does not depend on aggregation propensity

S Rodrigues, M Anglada-Huguet, K Hochgräfe… - Journal of Molecular …, 2023 - Springer
The stereotypical progression of Tau pathology during Alzheimer disease has been
attributed to trans-neuronal spreading of misfolded Tau proteins, followed by prion-like …