Errors occurring during DNA replication can result in inaccurate replication, incomplete
replication, or re-replication, resulting in genome instability that can lead to diseases such as …

Kinetochores are large protein assemblies that connect chromosomes to microtubules of the
mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to …

Grapevine is one of the most economically important crops worldwide. However, the
previous versions of the grapevine reference genome tipically consist of thousands of …

The centromere represents a single region in most eukaryotic chromosomes. However,
several plant and animal lineages assemble holocentromeres along the entire chromosome …

Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the
eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot …

Since discovery of the centromere-specific histone H3 variant CENP-A, centromeres have
come to be defined as chromatin structures that establish the assembly site for the complex …

Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and
attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and …

Faithful chromosome segregation in all eukaryotes relies on centromeres, the chromosomal
sites that recruit kinetochore proteins and mediate spindle attachment during cell division …

The structural maintenance of chromosome (SMC) complexes—cohesin and condensins—
are crucial for chromosome separation and compaction during cell division. During the …

Centromeres are rapidly evolving across eukaryotes, despite performing a conserved
function to ensure high-fidelity chromosome segregation. CENP-A chromatin is a hallmark of …