Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide and is often associated with aspects of metabolic syndrome. Despite its …

Nonalcoholic fatty liver disease (NAFLD) affects 25% of the global adult population and is
the most common chronic liver disease worldwide. Nonalcoholic steatohepatitis (NASH) is …

Cysteine is required for maintaining cellular redox homeostasis in both normal and
transformed cells. Deprivation of cysteine induces the iron-dependent form of cell death …

The spectrum of non-alcoholic fatty liver disease (NAFLD) ranges from simple hepatic
steatosis, commonly associated with obesity, to non-alcoholic steatohepatitis, which can …

With the increasing number of individuals with diabetes and obesity, nonalcoholic fatty liver
disease (NAFLD) is becoming increasingly prevalent, affecting one-quarter of adults …

Hepatocellular carcinoma (HCC) is the third most lethal cancer worldwide. The lack of
effective biomarkers for the early detection of HCC results in unsatisfactory curative …

Multimorbidity, the simultaneous presence of multiple chronic conditions, is an increasing
global health problem and research into its determinants is of high priority. We used …

Primary liver cancer (PLC) is the fourth most frequent cause of cancer-related death. The
high mortality rates arise from late diagnosis and the limited accuracy of diagnostic and …

Personal data for 108 individuals were collected during a 9-month period, including whole
genome sequences; clinical tests, metabolomes, proteomes, and microbiomes at three time …

Hepatocellular carcinoma has a poor prognosis due to its rapid development and early
metastasis. In this report, we characterized the metabolic features of hepatocellular …