The free radical diseases of prematurity: from cellular mechanisms to bedside
S Perrone, A Santacroce, M Longini… - Oxidative medicine …, 2018 - Wiley Online Library
During the perinatal period, free radicals (FRs) are involved in several physiological roles
such as the cellular responses to noxia, the defense against infectious agents, the regulation …
such as the cellular responses to noxia, the defense against infectious agents, the regulation …
Biomarkers of oxidative stress in the fetus and in the newborn
S Perrone, E Laschi, G Buonocore - Free Radical Biology and Medicine, 2019 - Elsevier
The dynamic field of perinatology entails ever-increasing search for molecular mechanisms
of neonatal diseases, especially in the domain of fetal growth and neurodevelopmental …
of neonatal diseases, especially in the domain of fetal growth and neurodevelopmental …
Oxidative stress and necrotizing enterocolitis: pathogenetic mechanisms, opportunities for intervention, and role of human milk
A Aceti, I Beghetti, S Martini, G Faldella… - … medicine and cellular …, 2018 - Wiley Online Library
This review will examine the role of oxidative stress (OS) in the pathogenesis of necrotizing
enterocolitis (NEC) and explore potential preventive and therapeutic antioxidant strategies …
enterocolitis (NEC) and explore potential preventive and therapeutic antioxidant strategies …
Vitamin A and retinoic acid exhibit protective effects on necrotizing enterocolitis by regulating intestinal flora and enhancing the intestinal epithelial barrier
S Xiao, Q Li, K Hu, Y He, Q Ai, L Hu, J Yu - Archives of medical research, 2018 - Elsevier
Background Exaggerated inflammation that characterizes necrotizing enterocolitis (NEC) is
caused by the invasion of pathogens through an immature intestinal barrier. Vitamin A (VA) …
caused by the invasion of pathogens through an immature intestinal barrier. Vitamin A (VA) …
miR‑34a increases inflammation and oxidative stress levels in patients with necrotizing enterocolitis by downregulating SIRT1 expression
H Zhu, Y Lin, Y Liu - Molecular Medicine Reports, 2021 - spandidos-publications.com
Abstract The miR‑34a/SIRT1 signaling axis is an important signaling axis in tumors and
diseases. Notably, low SIRT1 expression in the intestinal tissues of patients with necrotizing …
diseases. Notably, low SIRT1 expression in the intestinal tissues of patients with necrotizing …
The Emerging Roles of Ferroptosis in Neonatal Diseases
W Chen, D Zheng, C Yang - Journal of Inflammation Research, 2023 - Taylor & Francis
Ferroptosis is a novel type of programmed cell death involved in many diseases'
pathological processes. Ferroptosis is characterized by lipid peroxidation, reactive oxygen …
pathological processes. Ferroptosis is characterized by lipid peroxidation, reactive oxygen …
The role of oxidative stress on necrotizing enterocolitis in very low birth weight infants
S Perrone, M Luisa Tataranno… - Current pediatric …, 2014 - ingentaconnect.com
Necrotizing enterocolitis (NEC) is a devastating and common disease of very low birth
weight (VLBW) infants with a mortality rate of 10% to 50% and a significant cause of …
weight (VLBW) infants with a mortality rate of 10% to 50% and a significant cause of …
[HTML][HTML] Potential role of bile acids in the pathogenesis of necrotizing enterocolitis
J Yang, X Chen, T Liu, Y Shi - Life Sciences, 2024 - Elsevier
Necrotizing enterocolitis (NEC) is one of the most common acute gastrointestinal diseases in
preterm infants. Recent studies have found that NEC is not only caused by changes in the …
preterm infants. Recent studies have found that NEC is not only caused by changes in the …
[HTML][HTML] Role of NO and other vascular mediators in the etiopathogenesis of necrotizing enterocolitis
J Nair, S Lakshminrusimha - Frontiers in Bioscience-Scholar, 2019 - imrpress.com
The etio-pathogenesis of necrotizing enterocolitis (NEC) is complex and multifactorial.
Decades of research have not identified a definite etiology. Prematurity, enteral feeding …
Decades of research have not identified a definite etiology. Prematurity, enteral feeding …
Protective effects of dexpanthenol in an experimental model of necrotizing enterocolitis
A Karadag, R Ozdemir, A Kurt, H Parlakpinar… - Journal of pediatric …, 2015 - Elsevier
Background/purpose In pathogenesis of necrotizing enterocolitis (NEC), both oxidative
stress and inflammation are considerable risk factors. The study was designed to evaluate …
stress and inflammation are considerable risk factors. The study was designed to evaluate …