Natural source, bioactivity and synthesis of benzofuran derivatives

Y Miao, Y Hu, J Yang, T Liu, J Sun, X Wang - RSC advances, 2019 - pubs.rsc.org
Benzofuran compounds are a class of compounds that are ubiquitous in nature. Numerous
studies have shown that most benzofuran compounds have strong biological activities such …

Benzofuran derivatives and their anti-tubercular, anti-bacterial activities

Z Xu, S Zhao, Z Lv, L Feng, Y Wang, F Zhang… - European Journal of …, 2019 - Elsevier
Benzofuran is a fundamental structural unit in a variety of biologically active natural
products, and its derivatives display various biological properties. Some benzofuran …

One‐pot and two‐pot methods for chalcone derived pyrimidines synthesis and applications

S Farooq, Z Ngaini - Journal of Heterocyclic Chemistry, 2021 - Wiley Online Library
Chalcone‐derived pyrimidine is a well‐known heterocyclic compound that is commonly
present in ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) bio‐isosteres …

Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics–synthesis and properties

J Stefaniak, MG Nowak, M Wojciechowski… - Journal of Enzyme …, 2022 - Taylor & Francis
Abstract Glucosamine-6-phosphate synthase (GlcN-6-P synthase) is known as a promising
target for antimicrobial agents and antidiabetics. Several compounds of natural or synthetic …

Optoelectronic, DFT and current-voltage performance of new Schiff base 6-nitro-benzimidazole derivatives

K Upendranath, T Venkatesh, YA Nayaka… - Inorganic Chemistry …, 2022 - Elsevier
In the present work, we have synthesized a new Schiff base 6-nitro-benzimidazole derivative
(3a and 3b) and were confirmed by analytical and spectroscopic methods. TiO 2 …

An efficient p‐TSA catalyzed synthesis of some new substituted‐(5‐hydroxy‐3‐phenylisoxazol‐4‐yl)‐1, 3‐dimethyl‐1H‐chromeno [2, 3‐d] pyrimidine‐2, 4 (3H, 5H) …

SH Sukanya, T Venkatesh, SJA Rao… - Journal of Molecular …, 2022 - Elsevier
We have developed an easy and efficient protocol for the synthesis of a series of some novel
substituted-(5-hydroxy-3-phenylisoxazol-4-yl)-1, 3-dimethyl-1H-chromeno [2, 3-d] pyrimidine …

Therapeutic potential of naturally occurring benzofuran derivatives and hybrids of benzofurans with other pharmacophores as antibacterial agents

Z Xu, D Xu, W Zhou, X Zhang - Current Topics in Medicinal …, 2022 - ingentaconnect.com
Gram-positive and Gram-negative pathogens are able to evade the host immune system,
persist within the human host, and lead to severe disease and even death. At present …

Synthesis, crystal structure, antifungal activity, and docking study of difluoromethyl pyrazole derivatives

L Qiao, ZW Zhai, PP Cai, CX Tan… - Journal of …, 2019 - Wiley Online Library
Nine novel difluoromethylpyrazole acyl urea derivatives were synthesized via seven steps
conveniently. All the structures were determined by 1H‐NMR, 13C‐NMR, HRMS, and X‐ray …

[HTML][HTML] Synthesis of novel conjugated benzofuran-triazine derivatives: Antimicrobial and in-silico molecular docking studies

Z Riyahi, P Asadi, F Hassanzadeh, E Khodamoradi… - Heliyon, 2023 - cell.com
Two new developments of antibacterial agents, a series of benzofuran-triazine based
compounds (8a-8h) were designed and synthesized. The derivatives were prepared through …

[HTML][HTML] New Benzofuran–Pyrazole-Based Compounds as Promising Antimicrobial Agents: Design, Synthesis, DNA Gyrase B Inhibition, and In Silico Studies

SS Abd El-Karim, MM Anwar, YM Syam, HM Awad… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: The alarming rise in antibiotic resistance necessitates the discovery
of novel antimicrobial agents. This study aims to design, synthesize, and evaluate new …