Physical models of collective cell migration

R Alert, X Trepat - Annual Review of Condensed Matter Physics, 2020 - annualreviews.org
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Mechanisms of neural crest migration

A Szabó, R Mayor - Annual Review of Genetics, 2018 - annualreviews.org
Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

Cell migration guided by long-lived spatial memory

J d'Alessandro, A Barbier--Chebbah, V Cellerin… - Nature …, 2021 - nature.com
Living cells actively migrate in their environment to perform key biological functions—from
unicellular organisms looking for food to single cells such as fibroblasts, leukocytes or …

Learning the dynamics of cell–cell interactions in confined cell migration

DB Brückner, N Arlt, A Fink… - Proceedings of the …, 2021 - National Acad Sciences
The migratory dynamics of cells in physiological processes, ranging from wound healing to
cancer metastasis, rely on contact-mediated cell–cell interactions. These interactions play a …

Energetics of mesoscale cell turbulence in two-dimensional monolayers

SZ Lin, WY Zhang, D Bi, B Li, XQ Feng - Communications Physics, 2021 - nature.com
Investigation of energy mechanisms at the collective cell scale is a challenge for
understanding various biological processes, such as embryonic development and tumor …

Curvature induces active velocity waves in rotating spherical tissues

T Brandstätter, DB Brückner, YL Han, R Alert… - Nature …, 2023 - nature.com
The multicellular organization of diverse systems, including embryos, intestines, and tumors
relies on coordinated cell migration in curved environments. In these settings, cells establish …

Learning dynamical models of single and collective cell migration: a review

D Brückner, CP Broedersz - Reports on Progress in Physics, 2024 - iopscience.iop.org
Single and collective cell migration are fundamental processes critical for physiological
phenomena ranging from embryonic development and immune response to wound healing …

Inferring the dynamics of underdamped stochastic systems

DB Brückner, P Ronceray, CP Broedersz - Physical review letters, 2020 - APS
Many complex systems, ranging from migrating cells to animal groups, exhibit stochastic
dynamics described by the underdamped Langevin equation. Inferring such an equation of …

The role of vimentin in regulating cell invasive migration in dense cultures of breast carcinoma cells

Y Messica, A Laser-Azogui, T Volberg, Y Elisha… - Nano …, 2017 - ACS Publications
Cell migration and mechanics are tightly regulated by the integrated activities of the various
cytoskeletal networks. In cancer cells, cytoskeletal modulations have been implicated in the …

Spatially heterogeneous dynamics of cells in a growing tumor spheroid: Comparison between theory and experiments

S Sinha, AN Malmi-Kakkada, X Li, HS Samanta… - Soft matter, 2020 - pubs.rsc.org
Collective cell movement, characterized by multiple cells that are in contact for substantial
periods of time and undergo correlated motion, plays a central role in cancer and …