The role of long noncoding RNAs in hepatocellular carcinoma

Z Huang, JK Zhou, Y Peng, W He, C Huang - Molecular cancer, 2020 - Springer
Hepatocellular carcinoma (HCC) is the most frequent subtype of primary liver cancer and
one of the leading causes of cancer-related death worldwide. However, the molecular …

Epigenetic associations between lncRNA/circRNA and miRNA in hepatocellular carcinoma

TS Han, K Hur, HS Cho, HS Ban - Cancers, 2020 - mdpi.com
Simple Summary Non-coding RNAs such as microRNAs, long non-coding RNAs, and
circular RNAs contribute to the development and progression of hepatocellular carcinoma …

LncRNA MALAT1 induces colon cancer development by regulating miR‐129‐5p/HMGB1 axis

Q Wu, WY Meng, Y Jie, H Zhao - Journal of cellular physiology, 2018 - Wiley Online Library
Recent studies have exhibited significant roles of lncRNAs in various tumors' development,
including colon cancer. Our study focused on the biological roles of lncRNA MALAT1 in …

Role of lncRNAs in hepatocellular carcinoma

S Verma, BD Sahu, MN Mugale - Life Sciences, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is among the deadliest cancer in human malignancies. It is
the most common and severe type of primary liver cancer. However, the molecular …

LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years

C Tam, JH Wong, SKW Tsui, T Zuo, TF Chan… - Applied microbiology and …, 2019 - Springer
Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to
thousands of nucleotides. There are several major types of functional lncRNAs which …

The lncRNA MALAT1 contributes to non‐small cell lung cancer development via modulating miR‐124/STAT3 axis

S Li, Z Mei, HB Hu, X Zhang - Journal of Cellular Physiology, 2018 - Wiley Online Library
lncRNAs can exert many biological effects in several cancer types. MALAT1 is a kind of
lncRNA which is greatly overexpressed in several tumors including non‐small cell lung …

Long noncoding RNAs and human liver disease

JK DiStefano, GS Gerhard - Annual Review of Pathology …, 2022 - annualreviews.org
Long noncoding RNAs (lncRNAs) are pervasively transcribed in the genome, exhibit a
diverse range of biological functions, and exert effects through a variety of mechanisms. The …

Targeting long non-coding RNAs in cancer therapy using CRISPR-Cas9 technology: a novel paradigm for precision oncology

RK Mahato, S Bhattacharya, N Khullar, IS Sidhu… - Journal of …, 2024 - Elsevier
Cancer is the second leading cause of death worldwide, despite recent advances in its
identification and management. To improve cancer patient diagnosis and care, it is …

Downregulation of HULC induces ferroptosis in hepatocellular carcinoma via targeting of the miR‐3200‐5p/ATF4 axis

L Guan, F Wang, M Wang, S Han, Z Cui… - Oxidative Medicine …, 2022 - Wiley Online Library
Hepatocellular carcinoma is a malignant tumor that poses a serious threat to human health.
Ferroptosis, which represents an identified type of regulated iron‐dependent cell death, may …

[HTML][HTML] HMGA2 regulation by miRNAs in cancer: affecting cancer hallmarks and therapy response

M Hashemi, M Rashidi, K Hushmandi… - Pharmacological …, 2023 - Elsevier
High mobility group A 2 (HMGA2) is a protein that modulates the structure of chromatin in the
nucleus. Importantly, aberrant expression of HMGA2 occurs during carcinogenesis, and this …