Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …

Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

Objective To investigate the efficacy and safety of the interleukin-6 receptor antibody
tocilizumab in patients with Takayasu arteritis (TAK). Methods Patients with TAK who had …

Abstract Purpose of Review Giant cell arteritis (GCA) and Takayasu arteritis (TAK) are auto-
inflammatory and autoimmune diseases with a highly selective tissue tropism for medium …

The pharmacotherapy of Takayasu arteritis (TAK) with disease-modifying anti-rheumatic
drugs (DMARDs) is an evolving area. A systematic review of Scopus, Web of Science …

Takayasu arteritis is an idiopathic granulomatous vasculitis of the aorta and its main
branches and it constitutes one of the more common vasculitides in children. Inflammation …

Although outcomes in Takayasu arteritis (TAK) are improving, diagnosis is typically delayed
and significant arterial injury accrues. While wider use of non-invasive imaging is impacting …

Objective Tumor necrosis factor (TNF) alpha and interleukin‐17 (IL‐17) are thought to be
involved in the pathogenesis of Takayasu arteritis (TAK), and TNF inhibitors (TNFi) are …

Two vasculitides, giant cell arteritis (GCA) and Takayasu arteritis (TAK), are recognized as
autoimmune and autoinflammatory diseases that manifest exclusively within the aorta and …

Autoimmune diseases can afflict every organ system, including blood vessels that are
critically important for host survival. The most frequent autoimmune vasculitis is giant cell …