The prevalence of obesity has increased worldwide over the past few decades. In 2013, the
prevalence of obesity exceeded the 50% of the adult population in some countries from …

The pro-inflammatory state of the visceral adipose tissue (VAT) is supposed to accelerate
cardiovascular (CV) and metabolic diseases in obese subjects. Some studies have recently …

Purposeful weight loss continues to be the primary focus for treating obesity. However, this
strategy appears to be inadequate as obesity rates continue to rise and a myriad of benefits …

Patients with type 2 diabetes mellitus suffer from dysregulation of a plethora of
cardiovascular and metabolic functions, including dysglycaemia, dyslipidaemia, arterial …

1704 Circulation Research May 27, 2016 of epigenetic mechanisms contributing to
macrovascular disease in diabetes. The authors highlight the recent identification of …

In recent years, different subphenotypes of obesity have been described, including
metabolically healthy obesity (MHO), in which a proportion of obese individuals, despite …

Despite the strong and consistent evidence supporting that a high physical fitness (PF) level
at any age is a major predictor of a healthier metabolic profile, major studies focused on the …

Background Individuals with metabolic syndrome (MetS) are at a greater risk for developing
atherosclerotic cardiovascular disease (ASCVD) than those without MetS, due to underlying …

Objective We aimed to characterize metabolic status by body mass index (BMI) status.
Methods The CRONICAS longitudinal study was performed in an age-and-sex stratified …

Obesity and obesity-related diseases [type 2 diabetes, cardiovascular disease (CVD), and
cancer] are becoming more common, which is a major public health concern. Metabolically …