The epidemiology of bacterial meningitis has changed as a result of the widespread use of
conjugate vaccines and preventive antimicrobial treatment of pregnant women. Given the …

Acute community-acquired bacterial meningitis (ABM) in children continues to have high
rates of neurological morbidity and mortality despite the overall declining rates of infection …

Bacterial meningitis is a severe infectious disease of the membranes lining the brain
resulting in a high mortality and morbidity throughout the world. In the past decades the …

The microbiology of acute otitis media (AOM) is linked to the nasopharyngeal commensal
flora. This respiratory ecosystem undergoes various selective pressures, such as antibiotic …

Bacterial meningitis is among the top ten causes of infectious disease-related deaths
worldwide, with up to half of the survivors left with permanent neurological sequelae. The …

Otitis media typically presents as either acute otitis media (AOM), with symptoms including
fever, otalgia, otorrhoea or irritability and short duration; or as otitis media with effusion …

Importance Clinicians often risk stratify young febrile infants for invasive bacterial infections
(IBIs), defined as bacteremia and/or bacterial meningitis, using complete blood cell count …

Bacterial infections of the central nervous system (CNS) continue to be an important cause
of morbidity and mortality in children. The spectrum of bacterial infection of CNS includes; …

Bacterial meningitis is a severe, life-threatening infection of the central nervous system that
requires immediate medical attention. Even with appropriate treatment, morbidity and …

Although the annual incidence of bacterial meningitis in the United States is declining, it
remains a medical emergency with a potential for high morbidity and mortality. Clinical signs …