The aryl hydrocarbon receptor (AhR), discovered 46 years ago, is a transcript factor member
of the basic helix-loop-helix Per-ARNT-SIM (bHLH-PAS) family deeply implicated in health …

Sporadic late-onset Alzheimer's disease (AD) is the most frequent cause of dementia
associated with aging. Due to the progressive aging of the population, AD is becoming a …

Objective The extent to which tryptophan (Trp) metabolism alterations explain or influence
the outcome of inflammatory bowel diseases (IBDs) is still unclear. However, several Trp …

Persistent organic pollutants (POPs) are a diverse family of contaminants that show
widespread global dispersion and bioaccumulation. Humans are continuously exposed to …

For decades, activation of Aryl Hydrocarbon Receptor (AhR) was excluded from
consideration as a therapeutic approach due to the potential toxic effects of AhR ligands and …

Persistent organic pollutants (POPs) released from plastics into water, soil and air are
significant environmental and health problem. Continuous exposure of humans to these …

Introduction The activation of the kynurenine pathway in cancer progression and metastasis
through immunomodulatory pathways has drawn attention to the potential for kynurenine …

Bisphenol A (BPA) is an industrial raw material widely used in water bottles, medical devices
and food packaging, and is now ubiquitous in the environment. However, the effects of BPA …

The aim of the present study was to evaluate the expression levels of the aryl hydrocarbon
receptor (AHR) and its target gene CYP1B1 and to correlate their expression with Wnt5a/b-β …

Background Gout is a common disease with high incidence due to unhealthy diet and living
habits. Simiao Powder, as a classic formula consisted of four common herbs, has been …