Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2024 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

Subunit vaccines for Acinetobacter baumannii

N Yang, X Jin, C Zhu, F Gao, Z Weng, X Du… - Frontiers in …, 2023 - frontiersin.org
Acinetobacter baumannii is a gram-negative bacterium and a crucial opportunistic pathogen
in hospitals. A. baumannii infection has become a challenging problem in clinical practice …

Non-antibiotic prevention and treatment against Acinetobacter baumannii infection: Are vaccines and adjuvants effective strategies?

Y Hu, X Zhang, S Deng, C Yue, X Jia… - Frontiers in Microbiology, 2023 - frontiersin.org
Acinetobacter baumannii (A. baumannii) is a Gram-negative opportunistic pathogen widely
attached to the surface of medical instruments, making it one of the most common pathogens …

A novel mRNA multi-epitope vaccine of Acinetobacter baumannii based on multi-target protein design in immunoinformatic approach

Y Xu, F Zhu, Z Zhou, S Ma, P Zhang, C Tan, Y Luo… - BMC genomics, 2024 - Springer
Acinetobacter baumannii is a gram-negative bacillus prevalent in nature, capable of thriving
under various environmental conditions. As an opportunistic pathogen, it frequently causes …

Combination of BauA and OmpA elicit immunoprotection against Acinetobacter baumannii in a murine sepsis model

M Tamehri, I Rasooli, M Pishgahi, A Jahangiri… - Microbial …, 2022 - Elsevier
Aims Acinetobacter baumannii causes severe nosocomial infections and is a difficult-to-treat
pathogen due to the development of multidrug-resistant (MDR) strains. Vaccines and …

Identification and Pathogenicity of Emerging Fish Pathogen Acinetobacter johnsonii from a Disease Outbreak in Rainbow Trout (Oncorhynchus mykiss)

B Bi, Y Yuan, D Jia, W Jiang, H Yan… - Aquaculture …, 2023 - Wiley Online Library
In November 2017, a group of farmed rainbow trout (Oncorhynchus mykiss) died in Yunnan
Province, China, likely due to infection. These rainbow trout exhibited slow movement, no …

In silico design of a novel hybrid epitope-based antigen harboring highly exposed immunogenic peptides of BamA, OmpA, and Omp34 against Acinetobacter …

A Hessami, Z Mogharari, F Rahim, B Khalesi… - International …, 2024 - Elsevier
Acinetobacter baumannii, is among the highest priority bacteria according to the WHO
categorization which necessitate the exploration of alternative strategies such as …

[PDF][PDF] 美国牛蛙蝌蚪约氏不动杆菌的分离, 鉴定及耐药性分析

丁戈野, 李纯, 徐杨, 陈晓颖, 张秋实, 胡亮, 邓新兰… - 水产学报, 2024 - china-fishery.cn
为探明2023 年3 月初引起中国重庆市渝北区某牛蛙养殖场暴发疾病的原因,
本实验从患病美国牛蛙蝌蚪肝脏和肠道中分离优势菌, 采用形态学观察, 生理生化实验, 16S …

A two-protein cocktail elicits a protective immune response against Acinetobacter baumannii in a murine infection model

M Mirali, A Jahangiri, MJ Nadoushan, I Rasooli - Microbial Pathogenesis, 2023 - Elsevier
Purpose Due to its high drug resistance, Acinetobacter baumannii is a priority for new
therapeutic measures like vaccines. In this study, the protectivity of a combination cocktail of …

Combination of a Two-Protein Cocktail as a Vaccine Against Acinetobacter Baumannii Elicits a Protective Immune Response in Mice

M Mirali, A Jahangiri, M Jalali Nadoushan… - Available at SSRN … - papers.ssrn.com
Due to its high drug resistance, Acinetobacter baumannii stands as a priority need for new
therapeutic measures. Developing an effective vaccine is one of these measures. In this …