Autism spectrum disorder: focus on glutamatergic neurotransmission

M Montanari, G Martella, P Bonsi… - International Journal of …, 2022 - mdpi.com
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …

A meta-analysis of gut microbiota in children with autism

P Andreo-Martínez, M Rubio-Aparicio… - Journal of autism and …, 2022 - Springer
Previous studies have reported dysbiosis in the gut microbiota (GM) of children with autism
spectrum disorders (ASD), which may be a determining factor on child development through …

Maternal gestational diabetes mellitus and newborn DNA methylation: findings from the pregnancy and childhood epigenetics consortium

CG Howe, B Cox, R Fore, J Jungius, T Kvist… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Maternal gestational diabetes mellitus (GDM) has been associated with
adverse outcomes in the offspring. Growing evidence suggests that the epigenome may play …

Epigenetics and ADHD: reflections on current knowledge, research priorities and translational potential

CAM Cecil, JT Nigg - Molecular diagnosis & therapy, 2022 - Springer
Attention-deficit/hyperactivity disorder (ADHD) is a common and debilitating
neurodevelopmental disorder influenced by both genetic and environmental factors …

Autism spectrum disorder from the womb to adulthood: suggestions for a paradigm shift

C Panisi, FR Guerini, PM Abruzzo, F Balzola… - Journal of personalized …, 2021 - mdpi.com
The wide spectrum of unique needs and strengths of Autism Spectrum Disorders (ASD) is a
challenge for the worldwide healthcare system. With the plethora of information from …

An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder

BS Da Silva, EH Grevet, LCF Silva, JKN Ramos… - Discover Mental …, 2023 - Springer
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition
characterized by developmentally inappropriate symptoms of inattention and/or …

Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis

A Neumann, E Walton, S Alemany, C Cecil… - Translational …, 2020 - nature.com
Attention-deficit and hyperactivity disorder (ADHD) is a common childhood disorder with a
substantial genetic component. However, the extent to which epigenetic mechanisms play a …

Prenatal valproate in rodents as a tool to understand the neural underpinnings of social dysfunctions in autism spectrum disorder

AM Tartaglione, S Schiavi, G Calamandrei, V Trezza - Neuropharmacology, 2019 - Elsevier
Impairments in social interaction and verbal and non verbal communication are among the
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …

Brain-derived neurotrophic factor (BDNF) epigenomic modifications and brain-related phenotypes in humans: A systematic review

A Treble-Barna, LW Heinsberg, Z Stec… - Neuroscience & …, 2023 - Elsevier
Epigenomic modifications of the brain-derived neurotrophic factor (BDNF) gene have been
postulated to underlie the pathogenesis of neurodevelopmental, psychiatric, and …

DNA methylation is associated with prenatal exposure to sulfur dioxide and childhood attention-deficit hyperactivity disorder symptoms

YJ Choi, J Cho, YC Hong, D Lee, S Moon, SJ Park… - Scientific reports, 2023 - nature.com
Epigenetic influence plays a role in the association between exposure to air pollution and
attention deficit hyperactivity disorder (ADHD); however, research regarding sulfur dioxide …