Immunopathogenesis of Behcet's disease

B Tong, X Liu, J Xiao, G Su - Frontiers in immunology, 2019 - frontiersin.org
Behcet's disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology
characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions …

Risk factors, clinical features and treatment of Behçet's disease uveitis

Z Zhong, G Su, P Yang - Progress in Retinal and Eye Research, 2023 - Elsevier
Behçet's disease is a systemic vasculitis frequently associated with intraocular inflammation.
Recent findings identified independent clinical clusters in Behçet's disease, each involving …

Behçet's Syndrome

D Saadoun, B Bodaghi, P Cacoub - New England Journal of …, 2024 - Mass Medical Soc
Behçet’s Syndrome | New England Journal of Medicine Skip to main content Access provided
byKuopion Yliopistollinen Sairaala The New England Journal of Medicine homepage Advanced …

Behçet's disease physiopathology: a contemporary review

MJ Zeidan, D Saadoun, M Garrido, D Klatzmann… - Autoimmunity …, 2016 - Springer
Behçet's disease, also known as the Silk Road Disease, is a rare systemic vasculitis
disorder of unknown etiology. Recurrent attacks of acute inflammation characterize Behçet's …

Secukinumab in the treatment of noninfectious uveitis: results of three randomized, controlled clinical trials

AD Dick, I Tugal-Tutkun, S Foster, M Zierhut, SHM Liew… - Ophthalmology, 2013 - Elsevier
PURPOSE: To determine the efficacy and safety of different doses of secukinumab, a fully
human monoclonal antibody for targeted interleukin-17A blockade, in patients with …

Interleukin-17 in human inflammatory diseases

AG Shabgah, E Fattahi, FZ Shahneh - Advances in Dermatology and …, 2014 - termedia.pl
Human Th17 pro-inflammatory cells are currently defined as cells that produce IL-17A and F,
tumor necrosis factor (TNF)-α, IL-6, IL-21, IL-22 and IL-23. Recently discovered related …

Targeting JAK/STAT signalling in inflammatory skin diseases with small molecule inhibitors

K Welsch, J Holstein, A Laurence… - European journal of …, 2017 - Wiley Online Library
For most inflammatory skin diseases topical glucocorticosteroids and traditional oral
immunosuppressive drugs remain the principle treatment choices, but this has started to …

New insights into the pathogenesis of Behcet's disease

MP de Chambrun, B Wechsler, G Geri, P Cacoub… - Autoimmunity …, 2012 - Elsevier
Behçet's disease (BD) is a recurrent systemic inflammatory disorder of unknown origin
characterized by oral and genital mucous ulcer, uveitis, and skin lesions. Involvement of …

Temperature desynchronizes sugar and organic acid metabolism in ripening grapevine fruits and remodels their transcriptome

M Rienth, L Torregrosa, G Sarah, M Ardisson… - BMC Plant …, 2016 - Springer
Background Fruit composition at harvest is strongly dependent on the temperature during
the grapevine developmental cycle. This raises serious concerns regarding the …

Defining the human T helper 17 cell phenotype

F Annunziato, L Cosmi, F Liotta, E Maggi… - Trends in …, 2012 - cell.com
T helper (Th) 17 cells represent a third effector arm of CD4 T cells and complement the
function of the Th1 and Th2 cell lineages. Here, we provide an overview of the transcription …