Ammonia and urea transport across the rumen epithelium: a review

K Abdoun, F Stumpff, H Martens - Animal Health Research Reviews, 2006 - cambridge.org
The transport of nitrogen across the rumen epithelium is characterized by absorption of
ammonia from the rumen and by an influx of urea into the rumen. The transport rates of both …

Mouse models and the urinary concentrating mechanism in the new millennium

RA Fenton, MA Knepper - Physiological reviews, 2007 - journals.physiology.org
Our understanding of urinary concentrating and diluting mechanisms at the end of the 20th
century was based largely on data from renal micropuncture studies, isolated perfused …

Urea and renal function in the 21st century: insights from knockout mice

RA Fenton, MA Knepper - Journal of the American Society of …, 2007 - journals.lww.com
Since the turn of the 21st century, gene knockout mice have been created for all major urea
transporters that are expressed in the kidney: the collecting duct urea transporters UT-A1 …

Urea transport in the kidney

JD Klein, MA Blount, JM Sands - Comprehensive Physiology, 2011 - Wiley Online Library
Urea transport proteins were initially proposed to exist in the kidney in the late 1980s when
studies of urea permeability revealed values in excess of those predicted by simple lipid …

The emerging physiological roles of the SLC14A family of urea transporters

G Stewart - British journal of pharmacology, 2011 - Wiley Online Library
In mammals, urea is the main nitrogenous breakdown product of protein catabolism and is
produced in the liver. In certain tissues, the movement of urea across cell membranes is …

Mammalian urine concentration: a review of renal medullary architecture and membrane transporters

CM Nawata, TL Pannabecker - Journal of comparative physiology B, 2018 - Springer
Mammalian kidneys play an essential role in balancing internal water and salt
concentrations. When water needs to be conserved, the renal medulla produces …

Urea transporter physiology studied in knockout mice

X Li, G Chen, B Yang - Frontiers in physiology, 2012 - frontiersin.org
In mammals, there are two types of urea transporters; urea transporter (UT)-A and UT-B. The
UT-A transporters are mainly expressed in kidney epithelial cells while UT-B demonstrates a …

Mammalian urea transporters

CP Smith - Experimental physiology, 2009 - Wiley Online Library
Urea transporters (UTs) encoded by the Slc14a1 (UT‐B) and Slc14a2 (UT‐A) genes
mediate urea flux across cellular membranes. Considerable research has accrued detailing …

Urea transporters and renal function: lessons from knockout mice

RA Fenton - Current opinion in nephrology and hypertension, 2008 - journals.lww.com
Background In the mammalian nephron, urea reabsorption occurs by two distinct
mechanisms: a constitutive process that occurs in the proximal nephron accounting for …

A plate reader-based method for cell water permeability measurement

RA Fenton, HB Moeller, S Nielsen… - … of physiology-renal …, 2010 - journals.physiology.org
Cell volume and water permeability measurements in cultured mammalian cells are typically
conducted under a light microscope. Many of the employed approaches are time consuming …