Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Angiogenesis plays a critical role within the human body, from the early stages of life (ie,
embryonic development) to life-threatening diseases (eg, cancer, heart attack, stroke, wound …

Cancer arises in the context of an in vivo tumor microenvironment. This microenvironment is
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …

Cancer is a major health concern as the incidence is growing worldwide and still lacks
successful therapies. Plant-derived functional foods are getting considerable attention …

Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

Resveratrol, a naturally occurring polyphenol and phytoalexin, has received significant
attention in recent years due to its vast therapeutic effects including anticancer, antioxidant …

Polyphenols represent a structural class of mainly natural organic chemicals that contain
multiple phenol structural units. The beneficial properties of polyphenols have been …

Cancer is one of the most serious public health issues worldwide, demanding ongoing
efforts to find novel therapeutic agents and approaches. Amid growing interest in the …

Cancer is one of the most frequently diagnosed diseases, and despite the continuous efforts
in searching for new and more effective treatments, its morbidity and mortality remain a …