Keratinocyte PIEZO1 modulates cutaneous mechanosensation

AR Mikesell, O Isaeva, F Moehring, KE Sadler… - Elife, 2022 - elifesciences.org
Epidermal keratinocytes mediate touch sensation by detecting and encoding tactile
information to sensory neurons. However, the specific mechanotransducers that enable …

3D architecture and a bicellular mechanism of touch detection in mechanosensory corpuscle

YA Nikolaev, LH Ziolkowski, S Pang, WP Li… - Science …, 2023 - science.org
Mechanosensory corpuscles detect transient touch and vibration in the skin of vertebrates,
enabling precise sensation of the physical environment. The corpuscle contains a …

Lack of evidence for participation of TMEM150C in sensory mechanotransduction

J Ojeda-Alonso, V Bégay… - Journal of General …, 2022 - rupress.org
The membrane protein TMEM150C has been proposed to form a mechanosensitive ion
channel that is required for normal proprioceptor function. Here, we examined whether …

EXPLORING THE MOLECULAR BASIS OF TOUCH: A COMPARATIVE ANALYSIS OF GENE EXPRESSION IN SENSORY CORPUSCLE-RICH AND CORPUSCLE …

T Hart - uknowledge.uky.edu
Cutaneous touch is facilitated by discrete cellular complexes composed of non-neuronal
cells associated with mechanoreceptor neuron endings. The non-neuronal cells of these …