The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

Injury to the central nervous system (CNS) alters the molecular and cellular composition of
neural tissue and leads to glial scarring, which inhibits the regrowth of damaged axons …

The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …

All cells are influenced by mechanical forces. In the brain, force-generating and load-
bearing proteins twist, turn, ratchet, flex, compress, expand and bend to mediate neuronal …

Neurological disorders are one of the most important public health concerns in developed
countries. Established brain imaging techniques such as magnetic resonance imaging (MRI) …

Abstract Changes in tissue composition and cellular architecture have been associated with
neurological disease, and these in turn can affect biomechanical properties. Natural …

Magnetic resonance elastography (MRE) is an imaging technique for noninvasively and
quantitatively assessing tissue stiffness, akin to palpation. MRE is further able assess the …

Astroglia represent a class of heterogeneous, in form and function, cells known as
astrocytes, which provide for homoeostasis and defence of the central nervous system …

Just as the epigenome, the proteome and the electrophysiological properties of a cell
influence its function, so too do its intrinsic mechanical properties and its extrinsic …