Silk sericin-based materials for biomedical applications

J Liu, L Shi, Y Deng, M Zou, B Cai, Y Song, Z Wang… - Biomaterials, 2022 - Elsevier
Silk sericin, a natural protein extracted from silkworm cocoons, has been extensively studied
and utilized in the biomedical field because of its superior biological activities and …

A comprehensive review of recent advances in silk sericin: Extraction approaches, structure, biochemical characterization, and biomedical applications

M Saad, LM El-Samad, RA Gomaa… - International Journal of …, 2023 - Elsevier
Silks are natural polymers that have been widely used for centuries. Silk consists of a
filament core protein, termed fibroin, and a glue-like coating substance formed of sericin …

Design and performance of sericin/poly (vinyl alcohol) hydrogel as a drug delivery carrier for potential wound dressing application

G Tao, Y Wang, R Cai, H Chang, K Song, H Zuo… - Materials Science and …, 2019 - Elsevier
Developing a non-toxic, super-absorbent and antibacterial hydrogel as a skin wound
dressing is of significant importance. Sericin hydrogel is an ideal dressing material as it has …

Three-dimensionally printed silk-sericin-based hydrogel scaffold: a promising visualized dressing material for real-time monitoring of wounds

CS Chen, F Zeng, X Xiao, Z Wang, XL Li… - … applied materials & …, 2018 - ACS Publications
A wound dressing which can be convenient for real-time monitoring of wounds is particularly
attractive and user-friendly. In this study, a nature-originated silk-sericin-based (SS-based) …

[HTML][HTML] Microfibrillar-associated protein 4 in health and disease

R Kanaan, M Medlej-Hashim, R Jounblat, B Pilecki… - Matrix Biology, 2022 - Elsevier
Abstract Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix protein
belonging to the fibrinogen-related domain family. It has been localized to elastic fiber-rich …

Injectable hydrogel based on gellan gum/silk sericin for application as a retinal pigment epithelium cell carrier

S Kim, GY Jeon, SE Kim, SH Choe, SJ Kim, JS Seo… - ACS …, 2022 - ACS Publications
The damage to retinal pigment epithelium (RPE) cells can lead to vision loss and permanent
blindness. Therefore, an effective therapeutic strategy has emerged to replace damaged …

Beauvericin inhibits melanogenesis by regulating cAMP/PKA/CREB and LXR-α/p38 MAPK–mediated pathways

SE Lee, SH Park, SW Oh, JA Yoo, K Kwon, SJ Park… - Scientific Reports, 2018 - nature.com
Melanogenesis is the process of production of melanin pigments that are responsible for the
colors of skin, eye, and hair and provide protection from ultraviolet radiation. However …

Association of silk sericin and platelet lysate: Premises for the formulation of wound healing active medications

E Bari, S Perteghella, S Faragò, ML Torre - International journal of …, 2018 - Elsevier
Silk sericin (SS), a globular and water-soluble protein, showed to in vitro sustain the
proliferation of different mammalian cell lines, and to in vitro protect them from the oxidative …

LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression

X Chen, C Jiang, B Qin, G Liu, J Ji, X Sun, M Xu… - Cell death & …, 2017 - nature.com
Long noncoding RNAs (lncRNAs) have important roles in various biological processes. Our
previous work has revealed that dedifferentiation of retinal pigment epithelium (RPE) cells …

Sericin for tissue engineering

YY Jo, HY Kweon, JH Oh - Applied Sciences, 2020 - mdpi.com
Sericin is a 10-to-400 kDa hydrophilic protein with high serine content and is a silk
constituent together with fibroin. It is produced in the middle silk gland of the silkworm and …