[HTML][HTML] Radiomic biomarkers of tumor immune biology and immunotherapy response

JH Wang, KA Wahid, LV van Dijk, K Farahani… - Clinical and …, 2021 - Elsevier
Immunotherapies are leading to improved outcomes for many cancers, including those with
devastating prognoses. As therapies like immune checkpoint inhibitors (ICI) become a …

Apparent diffusion coefficient for distinguishing between malignant and benign lesions in the head and neck region: a systematic review and meta-analysis

A Surov, HJ Meyer, A Wienke - Frontiers in Oncology, 2020 - frontiersin.org
Background: The purpose of the present meta-analysis was to provide evident data about
use of apparent diffusion coefficient (ADC) values for distinguishing malignant and benign …

Apparent diffusion coefficient correlates with different histopathological features in several intrahepatic tumors

A Surov, KI Eger, J Potratz, S Gottschling, A Wienke… - European …, 2023 - Springer
Objectives To investigate associations between apparent diffusion coefficient (ADC) and cell
count, Ki 67, tumor-stroma ratio (TSR), and tumoral lymphocytes in different hepatic …

ADC-histogram analysis in head and neck squamous cell carcinoma. Associations with different histopathological features including expression of EGFR, VEGF, HIF …

HJ Meyer, L Leifels, G Hamerla, AK Höhn… - Magnetic Resonance …, 2018 - Elsevier
Objective Apparent diffusion coefficient (ADC) values derived from Diffusion-weighted
images are able to reflect tumor microstructure, such as cellularity, extracellular matrix or …

Machine-learning-based prediction of treatment outcomes using MR imaging-derived quantitative tumor information in patients with sinonasal squamous cell …

N Fujima, Y Shimizu, D Yoshida, S Kano, T Mizumachi… - Cancers, 2019 - mdpi.com
The purpose of this study was to determine the predictive power for treatment outcome of a
machine-learning algorithm combining magnetic resonance imaging (MRI)-derived data in …

Assessing immunotherapy with functional and molecular imaging and radiomics

R García-Figueiras, S Baleato-González, A Luna… - Radiographics, 2020 - pubs.rsna.org
Immunotherapy is changing the treatment paradigm for cancer and has introduced new
challenges in medical imaging. Because not all patients benefit from immunotherapy …

Correlation between human papillomavirus status and quantitative MR imaging parameters including diffusion-weighted imaging and texture features in …

M Ravanelli, A Grammatica… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The incidence of Oropharyngeal Squampus Cell
Carcinoma (OPSCC) cases is increasing especially in the Western countries due to the …

The utility of multiparametric MRI to characterize hypoxic tumor subvolumes in comparison to FMISO PET/CT. Consequences for diagnosis and chemoradiation …

N Wiedenmann, AL Grosu, M Büchert… - Radiotherapy and …, 2020 - Elsevier
Abstract Background and Purpose Hypoxia is an essential metabolic marker that determines
chemo-and radiation resistance in head-and-neck squamous cell carcinoma (HNSCC) …

Quantitative diffusion-weighted imaging analyses to predict response to neoadjuvant immunotherapy in patients with locally advanced head and neck carcinoma

HJ van der Hulst, JL Vos, R Tissier, LA Smit… - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy may induce early treatment response in head and neck
squamous cell carcinoma (HNSCC) for some patients. Routine imaging parameters fail to …

Soft tissue sarcomas: IVIM and DKI correlate with the expression of HIF-1α on direct comparison of MRI and pathological slices

X Li, L Yang, Q Wang, J Tao, Z Pan, S Wang - European Radiology, 2021 - Springer
Objective To investigate the correlation of intravoxel incoherent motion (IVIM) and diffusion
kurtosis imaging (DKI) parameters with the expression of HIF-1α in soft tissue sarcoma …