Zebrafish as a model vertebrate for investigating chemical toxicity

AJ Hill, H Teraoka, W Heideman… - Toxicological …, 2005 - academic.oup.com
Zebrafish (Danio rerio) has been a prominent model vertebrate in a variety of biological
disciplines. Substantial information gathered from developmental and genetic research …

Measuring anxiety in zebrafish: a critical review

C Maximino, TM de Brito, AW da Silva Batista… - Behavioural brain …, 2010 - Elsevier
Zebrafish are increasingly being used in behavioral neuroscience,
neuropsychopharmacology and neurotoxicology. Recently, behavioral screens used to …

[HTML][HTML] Toxicological effects of 6PPD and 6PPD quinone in zebrafish larvae

S Varshney, AH Gora, P Siriyappagouder… - Journal of Hazardous …, 2022 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is the most widely
used antioxidant in automobile tyres and many rubber products. We investigated the impact …

An evolutionarily conserved long noncoding RNA TUNA controls pluripotency and neural lineage commitment

N Lin, KY Chang, Z Li, K Gates, ZA Rana, J Dang… - Molecular cell, 2014 - cell.com
Here, we generated a genome-scale shRNA library targeting long intergenic noncoding
RNAs (lincRNAs) in the mouse. We performed an unbiased loss-of-function study in mouse …

The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio

P Haffter, M Granato, M Brand, MC Mullins… - …, 1996 - journals.biologists.com
In a large-scale screen, we isolated mutants displaying a specific visible phenotype in
embryos or early larvae of the zebrafish, Danio rerio. Males were mutagenized with …

Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons

JP Incardona, TK Collier, NL Scholz - Toxicology and applied …, 2004 - Elsevier
Fish embryos exposed to complex mixtures of polycyclic aromatic hydrocarbons (PAHs) from
petrogenic sources show a characteristic suite of abnormalities, including cardiac …

[图书][B] Zebrafish

C Nusslein-Volhard, R Dahm - 2002 - books.google.com
The zebrafish has become one of the most important model organisms to study biologial
processes in vivo. As a vertebrate that has many of the strengths of invertebrate model …

Animal models in epilepsy research: legacies and new directions

BP Grone, SC Baraban - Nature neuroscience, 2015 - nature.com
Human epilepsies encompass a wide variety of clinical, behavioral and electrical
manifestations. Correspondingly, studies of this disease in nonhuman animals have brought …

Advanced morphological—behavioral test platform reveals neurodevelopmental defects in embryonic zebrafish exposed to comprehensive suite of halogenated and …

PD Noyes, DE Haggard, GD Gonnerman… - Toxicological …, 2015 - academic.oup.com
The increased use of flammable plastics and electronic devices along with stricter fire safety
standards has led to the heavy use of flame retardant chemicals in many consumer …

Drinks like a fish: zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects

R Gerlai, M Lahav, S Guo, A Rosenthal - Pharmacology biochemistry and …, 2000 - Elsevier
Zebra fish may be an ideal vertebrate model system for numerous human diseases with
which the genetics and biological mechanisms of the disease may be studied. Zebra fish …