Sesamol, a major lignan in sesame seeds (Sesamum indicum): Anti-cancer properties and mechanisms of action

AF Majdalawieh, ZR Mansour - European journal of pharmacology, 2019 - Elsevier
Sesamol is a natural phenolic compound and a major lignan isolated from sesame seeds
(Sesamum indicum) and sesame oil. The therapeutic potential of sesamol was investigated …

[HTML][HTML] Sesame Seeds: A Nutrient-Rich Superfood

P Mostashari, A Mousavi Khaneghah - Foods, 2024 - mdpi.com
Sesame seeds (Sesamum indicum L.) have been cultivated for thousands of years and have
long been celebrated for their culinary versatility. Beyond their delightful nutty flavor and …

Platelets and their biomimetics for regenerative medicine and cancer therapies

Z Li, S Hu, K Cheng - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
Platelets, circulating blood cells derived from megakaryocytes, play a key role in various
physical activities, including coagulation, hemostasis, the body's innate immune response …

Biomimetic “nanoplatelets” as a targeted drug delivery platform for breast cancer theranostics

L Li, J Fu, X Wang, Q Chen, W Zhang… - ACS Applied Materials …, 2021 - ACS Publications
Breast cancer is a major threat to health and lives of females. Biomimetic nanotechnology
brought brighter hope for early diagnosis and treatment of breast cancer. Here, we proposed …

[HTML][HTML] Sesamol induces human hepatocellular carcinoma cells apoptosis by impairing mitochondrial function and suppressing autophagy

Z Liu, B Ren, Y Wang, C Zou, Q Qiao, Z Diao, Y Mi… - Scientific Reports, 2017 - nature.com
Sesamol, a nutritional phenolic antioxidant compound enriched in sesame seeds, has been
shown to have potential anticancer activities. This study aims at characterizing the antitumor …

Sesamol Enhances Cell Growth and the Biosynthesis and Accumulation of Docosahexaenoic Acid in the Microalga Crypthecodinium cohnii

B Liu, J Liu, P Sun, X Ma, Y Jiang… - Journal of agricultural …, 2015 - ACS Publications
Sesamol is a strong antioxidant phenolic compound found in sesame seed. It possesses the
ability to scavenge intracellular reactive oxygen species (ROS) and to inhibit malic enzyme …

[HTML][HTML] Mitoquinone (MitoQ) inhibits platelet activation steps by reducing ROS levels

D Méndez, D Arauna, F Fuentes… - International journal of …, 2020 - mdpi.com
Platelet activation plays a key role in cardiovascular diseases. The generation of
mitochondrial reactive oxygen species (ROS) has been described as a critical step required …

[HTML][HTML] Methotrexate Promotes Platelet Apoptosis via JNK-Mediated Mitochondrial Damage: Alleviation by N-Acetylcysteine and N-Acetylcysteine Amide

M Paul, M Hemshekhar, RM Thushara, MS Sundaram… - PloS one, 2015 - journals.plos.org
Thrombocytopenia in methotrexate (MTX)-treated cancer and rheumatoid arthritis (RA)
patients connotes the interference of MTX with platelets. Hence, it seemed appealing to …

[HTML][HTML] A comprehensive review of bioactive compounds and processing technology of sesame seed

X Ma, Z Wang, C Zheng, C Liu - Oil Crop Science, 2022 - Elsevier
Sesame seeds are promulgated as traditional high-quality edible oil crops, rich in lipid (40–
65%), protein (19–35%), and bioactive compounds. The review starts with bioactive …

An appraisal of current pharmacological perspectives of sesamol: A review

B Bosebabu, SP Cheruku… - Mini reviews in …, 2020 - ingentaconnect.com
Sesame (Sesamum indicum L.) seeds have been authenticated for its medicinal value in
both Chinese and Indian systems of medicine. Its numerous potential nutritional benefits are …