The CRISPR/Cas9 system is an RNA-based adaptive immune system in bacteria and
archaea. Various studies have shown that it is possible to target a wide range of human …

Many researchers are attempting to identify drugs that can be repurposed as effective
therapies for Alzheimer's disease (AD). Several recent studies have highlighted epidermal …

New EGFR inhibitor series of fifteen 5-chloro-3-hydroxymethyl-indole-2-carboxamide
derivatives has been designed, synthesized, and tested for antiproliferative activity against a …

Endoplasmic reticulum (ER) stress occurs when proteins are affected by various factors, fail
to fold properly into higher structures and accumulate in the lumen of the ER, which activates …

Cancer drug resistance has always been a major factor affecting the treatment of non-small
cell lung cancer, which reduces the quality of life of patients. The clustered regularly …

Antibody-drug conjugates (ADCs) represent a promising class of targeted cancer
therapeutics that combine the specificity of monoclonal antibodies with the potency of …

Renal cell carcinoma (RCC) is the most common form of kidney cancer. Systemic therapy is
the preferred method to eliminate residual cancer cells after surgery and prolong the survival …

Several different mechanisms are implicated in the resistance of lung cancer cells to
epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs), and only few have …

This review article provides a thorough exploration of the multifaceted landscape
surrounding CRISPR technology, with a specific focus on its evolution from genome editing …

Simple Summary There are several ways to mimic cancer cells features, one of those being
permanently editing their DNA. Even though cancer cells alone cannot represent the whole …