Low serum albumin: a neglected predictor in patients with cardiovascular disease

AA Manolis, TA Manolis, H Melita, DP Mikhailidis… - European Journal of …, 2022 - Elsevier
Albumin, the most abundant circulating protein in blood, is an essential protein which binds
and transports various drugs and substances, maintains the oncotic pressure of blood and …

Albumin in decompensated cirrhosis: new concepts and perspectives

M Bernardi, P Angeli, J Claria, R Moreau, P Gines… - Gut, 2020 - gut.bmj.com
The pathophysiological background of decompensated cirrhosis is characterised by a
systemic proinflammatory and pro-oxidant milieu that plays a major role in the development …

[HTML][HTML] Human serum albumin, systemic inflammation, and cirrhosis

V Arroyo, R García-Martinez, X Salvatella - Journal of hepatology, 2014 - Elsevier
Human serum albumin (HSA) is one of the most frequent treatments in patients with
decompensated cirrhosis. Prevention of paracentesis-induced circulatory dysfunction …

Albumin and its application in drug delivery

D Sleep - Expert opinion on drug delivery, 2015 - Taylor & Francis
Introduction: Rapid clearance of drugs from the body results in short therapeutic half-life and
is an integral property of many protein and peptide-based drugs. To maintain the desired …

Interactive association of drugs binding to human serum albumin

F Yang, Y Zhang, H Liang - International journal of molecular sciences, 2014 - mdpi.com
Human serum albumin (HSA) is an abundant plasma protein, which attracts great interest in
the pharmaceutical industry since it can bind a remarkable variety of drugs impacting their …

Clinical significance of serum albumin and implications of FcRn inhibitor treatment in IgG-mediated autoimmune disorders

ES Ward, D Gelinas, E Dreesen… - Frontiers in …, 2022 - frontiersin.org
Serum albumin (SA), the most abundant soluble protein in the body, maintains plasma
oncotic pressure and regulates the distribution of vascular fluid and has a range of other …

Role of albumin in diseases associated with severe systemic inflammation: pathophysiologic and clinical evidence in sepsis and in decompensated cirrhosis

A Artigas, J Wernerman, V Arroyo, JL Vincent… - Journal of critical care, 2016 - Elsevier
The metabolism of albumin in inflammatory states such as sepsis or major surgery is
complex and still not well characterized. Nevertheless, in inflammatory states, albumin …

Early combination of albumin with crystalloids administration might be beneficial for the survival of septic patients: a retrospective analysis from MIMIC-IV database

S Zhou, Z Zeng, H Wei, T Sha, S An - Annals of intensive care, 2021 - Springer
Background Fluid therapy is a cornerstone in the treatment of sepsis. Recently, the
guidelines have recommended the combined administration that using crystalloids plus …

Amyotrophic lateral sclerosis outcome measures and the role of albumin and creatinine: a population-based study

A Chiò, A Calvo, G Bovio, A Canosa, D Bertuzzo… - JAMA …, 2014 - jamanetwork.com
Importance There is an urgent need to identify reliable biomarkers of amyotrophic lateral
sclerosis (ALS) progression for clinical practice and pharmacological trials. Objectives To …

Fluid management in sepsis: The potential beneficial effects of albumin

JL Vincent, D De Backer, CJ Wiedermann - Journal of critical care, 2016 - Elsevier
Fluid administration is a key intervention in hemodynamic resuscitation. Timely expansion
(or restoration) of plasma volume may prevent tissue hypoxia and help to preserve organ …