Synopsis Propofol is an intravenous sedative hypnotic agent which rapidly and reliably
causes loss of consciousness. It is also associated with a quick and 'smooth'recovery, which …

Synopsis Propofol is a phenolic derivative that is structurally unrelated to other sedative
hypnotic agents. It has been used extensively as an anaesthetic agent, particularly in …

Background The authors studied the influence of age on the pharmacodynamics of propofol,
including characterization of the relation between plasma concentration and the time course …

Background The bispectral index (BIS), a value derived from the electroencephalograph
(EEG), has been proposed as a measure of anesthetic effect. To establish its utility for this …

The bispectral (BIS) index and 95% spectral edge frequency (SEF) of the
electroencephalograph (EEG) have been used to study the anesthetic and sedative effects …

Background Bispectral Index (BIS) has been used to measure sedation depth. Ideally, to
guide anesthetic management, range of BIS scores at different sedation levels should not …

Background The electroencephalogram (EEG) has been evaluated as a tool for measuring
depth of anesthesia, but the use of the EEG monitoring is still controversial. The current …

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Background The authors evaluated the effects of midazolam, propofol, thiopental, and
fentanyl on volunteer participants' memory for words and pictures at equisedative …

OBJECTIVES: Propofol has certain advantages over benzodiazepines plus narcotics as
sedation for endoscopy. In a few centers, propofol has reportedly been used in endoscopic …