Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment
Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of
developing psychiatric pathologies in later life. This link may be bridged by a defective …
developing psychiatric pathologies in later life. This link may be bridged by a defective …
Aceruloplasminemia with psychomotor excitement and neurological sign was improved by minocycline (case report)
M Hayashida, S Hashioka, H Miki, M Nagahama… - Medicine, 2016 - journals.lww.com
Aceruloplasminemia is an autosomal recessive disorder of iron metabolism caused by
mutations in the ceruloplasmin gene. Its prevalence is 1 in 2,000,000 people in Japan. This …
mutations in the ceruloplasmin gene. Its prevalence is 1 in 2,000,000 people in Japan. This …
Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and …
RL Openshaw, DM Thomson, JM Penninger… - …, 2017 - Springer
Rationale Members of the c-Jun N-terminal kinase (JNK) family of mitogen-activated protein
(MAP) kinases, and the upstream kinase MKK7, have all been strongly linked with synaptic …
(MAP) kinases, and the upstream kinase MKK7, have all been strongly linked with synaptic …
[HTML][HTML] Addictive neurons
SA Kodirov - Therapeutic targets for neurological diseases, 2017 - ncbi.nlm.nih.gov
Since the reward center is considered to be the area tegmentalis ventralis of the
hypothalamus, logically its neurons could mainly be responsible for addiction. However, the …
hypothalamus, logically its neurons could mainly be responsible for addiction. However, the …
[HTML][HTML] Behavioural and molecular characterisation of mice haploinsufficient for Map2k7, a schizophrenia risk gene
RL Openshaw - 2017 - theses.gla.ac.uk
Schizophrenia is a serious psychiatric disorder characterised by a breakdown in thought,
emotion and perception, which leads to alterations of normal behaviour and feelings, a …
emotion and perception, which leads to alterations of normal behaviour and feelings, a …