The transmembrane glycoprotein Mucin 1 (MUC1) is aberrantly glycosylated and
overexpressed in a variety of epithelial cancers, and plays a crucial role in progression of …

The interaction between respiratory pathogens and their hosts is complex and incompletely
understood. This is particularly true when pathogens encounter the mucus layer covering …

Purpose It has been reported that approximately 40% of ALI (acute lung injury) incidence
resulted from sepsis. Paclitaxel, as a classic anti-cancer drug, plays an important role in the …

The mucosal surfaces that form the boundary between the external environment and the
underlying tissue are protected by a mucus barrier. Mucin glycoproteins, both secreted and …

The family of cell surface (cs-) mucins are constitutively expressed at the cell surface by
nearly all epithelial cells, beneath the gel-mucin layer. All cs-mucin family members have …

Respiratory viruses are frequent causes of repeated common colds, bronchitis and
pneumonia, which often occur unpredictably as epidemics and pandemics. Despite those …

Mucus plays a pivotal role in protecting the respiratory tract against microbial infections. It
acts as a primary contact site to entrap microbes and facilitates their removal from the …

Airway mucus constitutes a thin layer of airway surface liquid with component
macromolecules that covers the luminal surface of the respiratory tract. The major function of …

Cell surface mucin (cs-mucin) glycoproteins are constitutively expressed at the surface of
respiratory epithelia where pathogens such as influenza A virus (IAV) gain entry into cells …

Respiratory viral infections represent the leading cause of hospitalization in infants and
young children worldwide, and the second cause of infant mortality. 1 Of all Disclosures: A …