Glucocorticoids (GCs) are endogenous hormones that are crucial for the homeostasis of the
organism and adaptation to the external environment. Because of their anti-inflammatory …

Nuclear receptor crosstalk can be defined as the interplay between different nuclear
receptors or between their overlapping signalling pathways. A subset of nuclear receptors …

Colitis has become a major health concern worldwide. The objective of the present study
was to determine the probiotic influence of different strains of B. pseudolongum (Bp7 and …

Sepsis is involved in~ 20% of annual global deaths. Despite decades of research, the
current management of sepsis remains supportive rather than curative. Clinical trials in …

Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic
responses to infection, thereby compromising host homeostasis. Activation of the …

Fasting metabolism and immunity are tightly linked; however, it is largely unknown how
immune cells contribute to metabolic homeostasis during fasting in healthy subjects. Here …

Glucocorticoids (GCs) are a class of steroid hormones that regulate key physiological
processes such as metabolism, immune function, and stress responses. The effects of GCs …

The normal stress response in humans is governed by the hypothalamic-pituitary-adrenal
(HPA) axis through heightened mechanisms during stress, raising blood levels of the …

Endogenous glucocorticoids (GCs) are steroid hormones that signal in virtually all cell types
to modulate tissue homeostasis throughout life. Also, synthetic GC derivatives …

Alcoholic liver injury is mainly caused by excessive alcohol consumption and has become a
global public health problem threatening human health. It is well known that Ganoderma …