Vertebral fractures due to osteoporosis commonly occur under non-traumatic loading
conditions. This problem affects more than 1 in 3 women and 1 in 10 men over a lifetime …

In this review, recent advances on the measurement and modeling of elastic properties of
cortical and trabecular bone are presented. Bone is a multifunctional material which among …

As our population ages, more individuals suffer from osteoporosis. This disease leads to
impaired trabecular architecture and increased fracture risk. It is essential to understand how …

Finite element (FE) analysis has been applied for the past 40 years to simulate the
mechanical behavior of bone. Although several validation studies have been performed on …

Proper quantitative characterization of microstructures, for the purpose of modeling the
effective properties, is discussed. This is a broad subject that covers different physical …

Preventing nontraumatic fractures in millions of patients with osteoporosis or metastatic
cancer may significantly reduce the associated morbidity and reduce health-care …

Abstract The International Society for Clinical Densitometry (ISCD) has developed new
official positions for the clinical use of quantitative computed tomography (QCT)-based finite …

The ability to evaluate fracture risk at an early time point is essential for improved
prognostics as well as enhanced treatment in cases of bone loss such as from osteoporosis …

The recent advances in microarchitectural bone imaging disclose the possibility to assess
both the apparent density and the trabecular microstructure of intact bones in a single …

Trabecular bone structure is crucial to normal mechanical behavior of bones. Studies have
shown that osteoporosis negatively affects trabecular bone structure, mainly by reducing …