Fluorescent probes for ferroptosis bioimaging: advances, challenges, and prospects

J Yin, J Zhan, Q Hu, S Huang, W Lin - Chemical Society Reviews, 2023 - pubs.rsc.org
Ferroptosis is a form of regulatory cell death distinct from caspase-dependent apoptosis and
plays an important role in life entities. Since ferroptosis involves a variety of complex …

Ferroptosis: mechanisms, biology and role in disease

X Jiang, BR Stockwell, M Conrad - Nature reviews Molecular cell …, 2021 - nature.com
The research field of ferroptosis has seen exponential growth over the past few years, since
the term was coined in 2012. This unique modality of cell death, driven by iron-dependent …

Ferroptosis: mechanisms and links with diseases

H Yan, T Zou, Q Tuo, S Xu, H Li, AA Belaidi… - Signal transduction and …, 2021 - nature.com
Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis,
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …

Ferroptosis: molecular mechanisms and health implications

D Tang, X Chen, R Kang, G Kroemer - Cell research, 2021 - nature.com
Cell death can be executed through different subroutines. Since the description of
ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been …

Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents

L Wu, C Huang, BP Emery, AC Sedgwick… - Chemical Society …, 2020 - pubs.rsc.org
In this tutorial review, we will explore recent advances in the construction and application of
Förster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The …

Fluorescent small organic probes for biosensing

X Tian, LC Murfin, L Wu, SE Lewis, TD James - Chemical science, 2021 - pubs.rsc.org
Small-molecule based fluorescent probes are increasingly important for the detection and
imaging of biological signaling molecules due to their simplicity, high selectivity and …

Ferroptosis detection: from approaches to applications

F Zeng, S Nijiati, L Tang, J Ye, Z Zhou… - Angewandte …, 2023 - Wiley Online Library
Understanding the intricate molecular machinery that governs ferroptosis and leveraging
this accumulating knowledge could facilitate disease prevention, diagnosis, treatment, and …

Recent progress in ferroptosis inducers for cancer therapy

C Liang, X Zhang, M Yang, X Dong - Advanced materials, 2019 - Wiley Online Library
Ferroptosis is a newly discovered form of regulated cell death that is the nexus between
metabolism, redox biology, and human health. Emerging evidence shows the potential of …

Synthetic ratiometric fluorescent probes for detection of ions

SH Park, N Kwon, JH Lee, J Yoon, I Shin - Chemical Society Reviews, 2020 - pubs.rsc.org
Metal cations and anions are essential for versatile physiological processes. Dysregulation
of specific ion levels in living organisms is known to have an adverse effect on normal …

Recent advances in small-molecule fluorescent probes for studying ferroptosis

YL Qi, HR Wang, LL Chen, YT Duan… - Chemical Society …, 2022 - pubs.rsc.org
Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …