Consanguinity and reproductive health among Arabs

GO Tadmouri, P Nair, T Obeid, MT Al Ali, N Al Khaja… - Reproductive health, 2009 - Springer
Consanguineous marriages have been practiced since the early existence of modern
humans. Until now consanguinity is widely practiced in several global communities with …

Consanguinity and inbreeding in health and disease in North African populations

L Romdhane, N Mezzi, Y Hamdi… - Annual review of …, 2019 - annualreviews.org
North Africa is defined as the geographical region separated from the rest of the continent by
the Sahara and from Europe by the Mediterranean Sea. The main demographic features of …

Consanguineous marriages in Morocco and the consequence for the incidence of autosomal recessive disorders

IC Jaouad, SC Elalaoui, A Sbiti, F Elkerh… - Journal of biosocial …, 2009 - cambridge.org
Consanguineous marriage is traditionally common throughout Arab countries. This leads to
an increased birth prevalence of infants with recessive disorders, congenital malformations …

Consanguinity, endogamy, and genetic disorders in Tunisia

N Ben Halim, N Ben Alaya Bouafif, L Romdhane… - Journal of community …, 2013 - Springer
Consanguinity refers to marriages between individuals who share at least one common
ancestor. In clinical genetics, a consanguineous marriage is defined as a union between two …

Consanguinity and dysmorphology in Arabs

L Al-Gazali, H Hamamy - Human heredity, 2014 - karger.com
Incidence rates of congenital disorders among the 350 million inhabitants of Arab countries
could be influenced via the people's demographic and cultural characteristics. Arabs usually …

Founder mutations in Tunisia: implications for diagnosis in North Africa and Middle East

L Romdhane, R Kefi, H Azaiez, NB Halim… - Orphanet journal of rare …, 2012 - Springer
Abstract Background Tunisia is a North African country of 10 million inhabitants. The native
background population is Berber. However, throughout its history, Tunisia has been the site …

Disease burden and management of Crigler‐Najjar syndrome: Report of a world registry

SJ Aronson, N Junge, M Trabelsi, W Kelmemi… - Liver …, 2022 - Wiley Online Library
Results Clinical data of 221 CNS patients (46% female, severe phenotype n= 209) were
collected. At the time of analysis, 59 CNS patients were deceased. Mean serum total …

Primary immunodeficiencies in highly consanguineous North African populations

MR Barbouche, N Galal… - Annals of the New …, 2011 - Wiley Online Library
The study of inbred populations has contributed remarkably to the description of new
autosomal recessive primary immunodeficiencies (PIDs). Here, we examine the pattern of …

Genetic diseases in the Tunisian population

L Romdhane, S Abdelhak… - American Journal of …, 2011 - Wiley Online Library
Tunisia is one of the North African countries, geographically situated in a central position at
the crossroad between Africa and Europe. The demographic features of the Tunisian …

Consanguinity, genetic drift, and genetic diseases in populations with reduced numbers of founders

AH Bittles - Vogel and Motulsky's human genetics, 2010 - Springer
In western countries, consanguineous marriage often arouses curiosity and prejudice in
approximately equally measure, despite the fact that until the mid-nineteenth century cousin …