Tumor‐associated macrophages in liver cancer: from mechanisms to therapy

K Cheng, N Cai, J Zhu, X Yang, H Liang… - Cancer …, 2022 - Wiley Online Library
Multidimensional analyses have demonstrated the presence of a unique tumor
microenvironment (TME) in liver cancer. Tumor‐associated macrophages (TAMs) are …

Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities

Y Wen, J Lambrecht, C Ju, F Tacke - Cellular & molecular immunology, 2021 - nature.com
Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …

Alcohol-associated liver disease

B Mackowiak, Y Fu, L Maccioni… - The Journal of Clinical …, 2024 - Am Soc Clin Investig
Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

Cellular mechanisms of liver fibrosis

P Acharya, K Chouhan, S Weiskirchen… - Frontiers in …, 2021 - frontiersin.org
The liver is a central organ in the human body, coordinating several key metabolic roles. The
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …

[HTML][HTML] Control of human toxoplasmosis

NC Smith, C Goulart, JA Hayward, A Kupz… - International journal for …, 2021 - Elsevier
Toxoplasmosis is caused by Toxoplasma gondii, an apicomplexan parasite that is able to
infect any nucleated cell in any warm-blooded animal. Toxoplasma gondii infects around 2 …

Immunological mechanisms and therapeutic targets of fatty liver diseases

H Wang, W Mehal, LE Nagy, Y Rotman - Cellular & Molecular …, 2021 - nature.com
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …

Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting

MA Avila, JF Dufour, AL Gerbes, F Zoulim, R Bataller… - Gut, 2020 - gut.bmj.com
Alcohol-related liver disease (ALD), which includes a range of disorders of different severity
and is one of the most prevalent types of liver disease worldwide, has recently regained …

Hepatic macrophages: Key players in the development and progression of liver fibrosis

D Cheng, J Chai, H Wang, L Fu, S Peng… - Liver …, 2021 - Wiley Online Library
Hepatic fibrosis is a common pathological process involving persistent liver injury with
various etiologies and subsequent inflammatory responses that occur in chronic liver …

Functional roles of chemokine receptor CCR2 and its ligands in liver disease

S She, L Ren, P Chen, M Wang, D Chen… - Frontiers in …, 2022 - frontiersin.org
Chemokines are a family of cytokines that orchestrate the migration and positioning of
immune cells within tissues and are critical for the function of the immune system. CCR2 …

Pathogenesis, early diagnosis, and therapeutic management of alcoholic liver disease

LZ Kong, N Chandimali, YH Han, DH Lee… - International journal of …, 2019 - mdpi.com
Alcoholic liver disease (ALD) refers to the damages to the liver and its functions due to
alcohol overconsumption. It consists of fatty liver/steatosis, alcoholic hepatitis …