The importance of MRI for rectal cancer evaluation

MC Fernandes, MJ Gollub, G Brown - Surgical oncology, 2022 - Elsevier
Magnetic resonance imaging (MRI) has gained increasing importance in the management of
rectal cancer over the last two decades. The role of MRI in patients with rectal cancer has …

Risk of recurrence in patients with colon cancer stage II and III: a systematic review and meta-analysis of recent literature

C Böckelman, BE Engelmann, T Kaprio… - Acta …, 2015 - Taylor & Francis
Background. Adjuvant chemotherapy is established routine therapy for colon cancer (CC)
patients with radically resected stage III and 'high-risk'stage II disease. The decision on …

Mucinous and signet-ring cell colorectal cancers differ from classical adenocarcinomas in tumor biology and prognosis

U Nitsche, A Zimmermann, C Späth, T Müller… - Annals of …, 2013 - journals.lww.com
Objectives: To define the prognostic value of different histological subtypes of colorectal
cancer. Background: Most colorectal cancers are classical adenocarcinomas (AC). Less …

Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer

M Maak, I Simon, U Nitsche, P Roepman… - Annals of …, 2013 - journals.lww.com
Objectives: The aim of this study was to independently validate a genomic signature
developed both to assess recurrence risk in stage II patients and to assist in treatment …

Genomic classifier ColoPrint predicts recurrence in stage II colorectal cancer patients more accurately than clinical factors

S Kopetz, J Tabernero, R Rosenberg, ZQ Jiang… - The …, 2015 - academic.oup.com
Background. Approximately 20% of patients with stage II colorectal cancer will experience a
relapse. Current clinical-pathologic stratification factors do not allow clear identification of …

Automated analysis of lymphocytic infiltration, tumor budding, and their spatial relationship improves prognostic accuracy in colorectal cancer

IP Nearchou, K Lillard, CG Gavriel, H Ueno… - Cancer immunology …, 2019 - AACR
Both immune profiling and tumor budding significantly correlate with colorectal cancer
patient outcome but are traditionally reported independently. This study evaluated the …

The colorectal cancer lipidome: identification of a robust tumor-specific lipid species signature

J Ecker, E Benedetti, ASD Kindt, M Höring, M Perl… - Gastroenterology, 2021 - Elsevier
Objective Lipidomic changes were causally linked to metabolic diseases, but the scenario
for colorectal cancer (CRC) is less clear. We investigated the CRC lipidome for putative …

Biomarkers in precision therapy in colorectal cancer

MS Reimers, ECM Zeestraten, PJK Kuppen… - Gastroenterology …, 2013 - academic.oup.com
Colorectal cancer (CRC) is the most commonly diagnosed cancer in Europe. Because CRC
is also a major cause of cancer-related deaths worldwide, a lot of research has been …

Activation of the PI3K/AKT pathway correlates with prognosis in stage II colon cancer

K Malinowsky, U Nitsche, KP Janssen, FG Bader… - British journal of …, 2014 - nature.com
Background: Patients with UICC/AJCC stage II colon cancer have a high 5-year overall
survival rate after surgery. Nevertheless, a significant subgroup of patients develops tumour …

[HTML][HTML] Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer

L Kistner, D Doll, A Holtorf, U Nitsche, KP Janssen - Oncotarget, 2017 - ncbi.nlm.nih.gov
Tumor-infiltrating T-cells are strongly associated with prognosis in colorectal cancer, but the
mechanisms governing intratumoral lymphocyte recruitment are unclear. We investigated …